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diagnosis management anemia blood myelodysplastic product reactions treatment criteria enterocolitis hematololgy leukemia myelodysplasia nec neutropenic syndrome syndromes transfusion transfusions
Aplastic Anemia Summary • Definition • Pathophysiology • DDx: AA vs Hypocellular MDS • Expectation •
Aplastic Anemia ... vs Hypocellular MDS ... @ZhuoerXie #Aplastic ... Anemia #diagnosis #oncology ... #hematololgy
Aplastic Anemia - Illness Script Signs and symptoms: • Recurrent infections from neutropenia • Mucosal bleeding from
Aplastic Anemia ... neutropenia • Mucosal bleeding ... Can progress to MDS ... Medicine @SCVMCMed #Aplastic ... management #treatment #hematology
Diagnostic criteria for Neutropenic Enterocolitis (NEC) Major Criteria: • Neutropenia (ANC <500 x 10^9 cells/L) • Bowel
Criteria: • Abdominal ... distention • Abdominal ... Diarrhea • Lower Gl bleeding ... Diagnosis #criteria #hematology ... #oncology
Myelodysplastic Syndrome (MD) - Diagnosis and Management Summary myelo (marrow) -dys- (abnormal) -plastic (shape) = funny-shaped cells
Myelodysplastic Syndrome (MD ... dys- (abnormal) -plastic ... Myelodysplastic #Syndrome #MDS ... Management #treatment #hematology ... #oncology
Aplastic Anemia - Overview Who? • M = F • 3 peaks: 1) Childhood 2) 15-25 years 3) >60 years What? • Aplastic anemia
ecchymoses, mucosal bleeding ... myelodysplastic syndrome (MDS ... Hypocellular/Hypoplastic MDS ... #Anemia #oncology ... #hematology #diagnosis
Leukemias Overview: ALL, CML, AML, APML, CLL Acute leukemias > 20% blasts in the peripheral blood smear
Symptoms: • Malaise, bleeding ... , weight loss, abdominal ... night sweats, bleeding ... #Leukemia #Hematology ... #Oncology #Diagnosis
Myelodysplastic Syndromes (MDS) What? Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
unusual bruising or bleeding ... are caused by bleeding ... Causes • Anemia • Aplastic ... Syndromes #diagnosis #hematology ... #oncology
Blood Transfusion Reactions Immune Mediated: • Febrile Non-Hemolytic Transfusion Reaction (FNHTR): Most common immune reaction to transfusion.
Injury (TRALI): Leading ... due to marrow aplasia ... coagulopathy & ↑bleeding ... infographic by Nick Mark MD ... diagnosis #management #hematology
Blood Product Transfusions One Pager Summary Type and screen - determines blood type and detects in recipient
Injury (TRALI): Leading ... due to marrow aplasia ... coagulopathy & ↑bleeding ... by Nick Mark MD ... diagnosis #management #hematology
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