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diagnosis differential oncology management anemia aplastic basophilia basophils bruising coagulation cryofibrinogenemia dic disseminated hemostasis intravascular mds myelodysplasia myelodysplastic platelet rheumatology
Causes of Thrombocytopenia and Platelet Disorders - Differential Diagnosis and Workup History: - Prior platelet count, family
- History of bleeding ... epistaxis, gingival bleeding ... plateletcount), peripheral blood ... or if a primary hematologic ... #Workup #hematology
Leukemias Overview: ALL, CML, AML, APML, CLL Acute leukemias > 20% blasts in the peripheral blood smear
the peripheral blood ... Blast cells - Blood ... blast cells - Blood ... -> AML: Blast crises ... #Hematology #Oncology
Basophilia - Differential Diagnosis Framework Basophils < 1% of the total white blood cell count Basophils function similarly
the total white blood ... Myeloproliferative Disorders ... Chickenpox Other Causes ... Differential #Diagnosis #causes ... #hematology #basophils
Disseminated Intravascular Coagulation (DIC) Overview Increased Clotting and Consumption of Clotting Factors Findings: • Bleeding • Recent history
promyelocytic leukemia ... ABO incompatible blood ... Treat primary cause ... Coagulation #diagnosis #causes ... treatment #management #hematology
Bleeding and Bruising - Disorders of Hemostasis - Differential Diagnosis Framework == Quantitative or Qualitative defect in
- Disorders of ... of a platelet disorder ... gingivitis or gingival leukemic ... discern these causes ... Differential #Diagnosis #Hematology
Myelodysplastic Syndromes (MDS) What? Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
are a group of disorders ... caused by blood ... by bleeding (petechiae ... • Hairy Cell Leukemia ... Syndromes #diagnosis #hematology
Cryofibrinogenemia Summary Cryofibrinogenemia Epidemiology: • 40-70 years with a modest female predominance Cryofibrinogenemia: • The precipitation of a
which can plug blood ... Paradoxical spontaneous bleeding ... cryoglobulinemia Associated Disorders ... cryoglobulins • Negative causes ... #hematology
Aplastic Anemia - Overview Who? • M = F • 3 peaks: 1) Childhood 2) 15-25 years 3) >60 years What? • Aplastic anemia
ecchymoses, mucosal bleeding ... and petechiae Causes ... virus (EBV) • Leukemia ... result from low blood ... Anemia #oncology #hematology
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