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diagnosis differential management oncology anemia product reactions thrombocytopenia workup acronym algorithm approach basophilia basophils bruising chronic classification cll coagulation cryofibrinogenemia
Causes of Thrombocytopenia and Platelet Disorders - Differential Diagnosis and Workup History: - Prior platelet count, family
- History of bleeding ... epistaxis, gingival bleeding ... plateletcount), peripheral blood ... or if a primary hematologic ... #Workup #hematology
Leukemias Overview: ALL, CML, AML, APML, CLL Acute leukemias > 20% blasts in the peripheral blood smear
the peripheral blood ... Blast cells - Blood ... blast cells - Blood ... -> AML: Blast crises ... #Hematology #Oncology
Overall Approach to Anemia - Differential Diagnosis Algorithm Blood Loss • Acute Bleed - Normocytic / Normochromic
Diagnosis Algorithm Blood ... Deficiency • Aplastic ... • RBC Membrane Disorder ... Diagnosis #Algorithm #Causes ... #Hematology
Basophilia - Differential Diagnosis Framework Basophils < 1% of the total white blood cell count Basophils function similarly
the total white blood ... Myeloproliferative Disorders ... Chickenpox Other Causes ... Differential #Diagnosis #causes ... #hematology #basophils
Aplastic Anemia - Overview Who? • M = F • 3 peaks: 1) Childhood 2) 15-25 years 3) >60 years What? • Aplastic anemia
ecchymoses, mucosal bleeding ... and petechiae Causes ... virus (EBV) • Leukemia ... result from low blood ... Anemia #oncology #hematology
PLATELETS Mnemonic for Causes of Thrombocytopenia P - Platelet Disorders (DIC, ITP, TTP) L - Leukemia, Lymphoma A -
PLATELETS Mnemonic for Causes ... P - Platelet Disorders ... ITP, TTP) L - Leukemia ... Lymphoma A - Aplastic ... Differential #Diagnosis #Hematology
Chronic Lymphocytic Leukemia - Summary Cancer affecting lymphocytes/Mature B cell neoplasm • Lymphocytes accumulate in large numbers
Chronic Lymphocytic Leukemia ... lymphoproliferative disorders ... Lymphocytosis: Absolute blood ... Pure red cell aplasia ... workup #oncology #hematology
Myelodysplastic Syndromes (MDS) What? Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
are a group of disorders ... caused by blood ... • Anemia • Aplastic ... • Hairy Cell Leukemia ... Syndromes #diagnosis #hematology
Disseminated Intravascular Coagulation (DIC) Overview Increased Clotting and Consumption of Clotting Factors Findings: • Bleeding • Recent history
promyelocytic leukemia ... ABO incompatible blood ... Treat primary cause ... Coagulation #diagnosis #causes ... treatment #management #hematology
Bleeding and Bruising - Disorders of Hemostasis - Differential Diagnosis Framework == Quantitative or Qualitative defect in
- Disorders of ... of a platelet disorder ... gingivitis or gingival leukemic ... discern these causes ... Differential #Diagnosis #Hematology
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