44 results
diagnosis differential management algorithm oncology workup classification deficiency rheumatology atlas cirrhosis gastroenterology hemolysis hepatopulmonary iron leukemia liver macrocytic mcv morphology
Diagnostic Framework for Hemolysis - Intravascular vs Extravascular Causes Intravascular Hemolysis: • Mechanical Trauma (Microangiopathic hemolytic anemia):
Extravascular Causes ... anemia): ... lymphoproliferative disorders ... differential #diagnosis #hematology ... #anemia
Red Blood Cell (RBC) Morphology Atlas • Microcytic - Iron-deficiency anemia, Thalassemia, Sideroblastic anemia, Lead poisoning
Red Blood Cell ( ... Myelodysplastic syndrome ... Liver diseases, Bleeding ... uremic syndrome ... #differential #hematology
Causes of Thrombocytopenia and Platelet Disorders - Differential Diagnosis and Workup History: - Prior platelet count, family
- History of bleeding ... epistaxis, gingival bleeding ... plateletcount), peripheral blood ... changes), high MCV anemia ... #Workup #hematology
Causes of Thrombocytosis - Differential Diagnosis Secondary Thrombocytosis (a.k.a Reactive Thrombocytosis): • Acute infection • Solid organ
malignancies • Anemia ... iron deficiency, hemolysis ... Chronic inflammatory disorders ... Myelodysplastic syndrome ... #hematology #secondary
Causes of Anemia by Mean Corpuscular Volume (MCV) - Differential Diagnosis Algorithm Low Mean Corpuscular Volume (<80
Causes of Anemia ... 80-100 fL) • Bleeding ... • Hemolysis ... Diagnosis #Algorithm #Causes ... #Hematology
Red Blood Cell (RBC) Morphology Microcytic RBC: Pyridoxine deficiency, Thalassemia, Iron deficiency anemia, Chronic disease anemia (sometimes),
Red Blood Cell ( ... disease, McLeod blood ... Microangiopathic Hemolytic ... Unstable hemoglobin disorders ... differential #diagnosis #hematology
Causes of Iron Deficiency • Diet: ↓ Intake, e.g. vegan, Malnutrition, Polyphenol / tannins, ↓ Vitamin
Causes of Iron Deficiency ... Celiac, Enteritis, Bleeding ... hepcidin) • Others: Hemolysis ... Iron metabolism disorders ... differential #diagnosis #anemia
Purpura - Differential Diagnosis Framework Non-blanchable, dark red to purple, hemorrhagic skin lesions that result from leakage
DIC/TTP/HUS - Hemolytic ... anemia - Splenomegaly ... Kasabach-Merritt syndrome ... Gardner-Diamond syndrome ... Differential #Diagnosis #hematology
Inherited Non-hemolytic Disorders of Hyperbilirubinemia == Disorders of Conjugation == Gilbert Syndrome: • 5-10% of the population
Inherited Non-hemolytic ... without evidence of hemolysis ... and stress may cause ... bilirubin in the blood ... Congenital #bilirubin #hepatology
Causes of Anemia with elevated Mean Corpuscular Volume (MCV) - Differential Diagnosis Algorithm Normal Blood Smear •
Causes of Anemia ... Algorithm Normal Blood ... • Small Bowel Disorder ... Myelodysplastic Syndromes ... #Hematology
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