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diagnosis differential management algorithm oncology rheumatology treatment bruising cirrhosis classification gastroenterology hemolytic hepatopulmonary intravascular leukemia product pulmonary reactions workup agglutinin
Causes of Bleeding / Bruising - Differential Diagnosis Algorithm Thrombocytopenia - Quantitative Defect • Decreased Production •
Causes of Bleeding ... Sequestration Disordered ... Connective Tissue Disorders ... Coagulation #Bleeding ... #Hematology
Causes of Thrombocytopenia and Platelet Disorders - Differential Diagnosis and Workup History: - Prior platelet count, family
- History of bleeding ... epistaxis, gingival bleeding ... plateletcount), peripheral blood ... changes), high MCV anemia ... #Workup #hematology
Purpura - Differential Diagnosis Framework Non-blanchable, dark red to purple, hemorrhagic skin lesions that result from leakage
- Hemolytic anemia ... Kasabach-Merritt syndrome ... Retiform purpura - Protein ... Gardner-Diamond syndrome ... Differential #Diagnosis #hematology
Causes of Anemia with elevated Mean Corpuscular Volume (MCV) - Differential Diagnosis Algorithm Normal Blood Smear •
Causes of Anemia ... Algorithm Normal Blood ... • Small Bowel Disorder ... Myelodysplastic Syndromes ... #Hematology
Overall Approach to Anemia - Differential Diagnosis Algorithm Blood Loss • Acute Bleed - Normocytic / Normochromic
Diagnosis Algorithm Blood ... • RBC Membrane Disorder ... RBC Metabolism Disorder ... Diagnosis #Algorithm #Causes ... #Hematology
Red Blood Cell (RBC) Morphology Atlas • Microcytic - Iron-deficiency anemia, Thalassemia, Sideroblastic anemia, Lead poisoning
Red Blood Cell ( ... Myelodysplastic syndrome ... Liver diseases, Bleeding ... Hemolytic uremic syndrome ... #differential #hematology
Causes of Thrombocytosis - Differential Diagnosis Secondary Thrombocytosis (a.k.a Reactive Thrombocytosis): • Acute infection • Solid organ
Causes of Thrombocytosis ... malignancies • Anemia ... Chronic inflammatory disorders ... Myelodysplastic syndrome ... #hematology #secondary
Myelodysplastic Syndromes (MDS) What? Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
are a group of disorders ... caused by blood ... unusual bruising or bleeding ... by bleeding (petechiae ... #diagnosis #hematology
Indications for Serum Protein Electrophoresis (SPEP) • Suspected multiple myeloma, Waldenström's macroglobulinemia, primary amyloidosis, or related
amyloidosis, or related disorder ... • New-onset anemia ... pain, abnormal bleeding ... on peripheral blood ... Electrophoresis #SPEP #Hematology
Inherited Non-hemolytic Disorders of Hyperbilirubinemia == Disorders of Conjugation == Gilbert Syndrome: • 5-10% of the population
hyperbilirubinemia syndrome ... and stress may cause ... bilirubin in the blood ... a canalicular protein ... Congenital #bilirubin #hepatology
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