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diagnosis differential management causes atlas classification leukemia morphology product reactions workup algorithm approach bloodcell calculation chronic disorders hodgkins index key
Overall Approach to Anemia - Differential Diagnosis Algorithm Blood Loss • Acute Bleed - Normocytic / Normochromic
Diagnosis Algorithm Blood ... Reticulocytes • Iron Deficiency ... • B12/Folate Deficiency ... • Aplastic Anemia ... Algorithm #Causes #Hematology
Red Blood Cell (RBC) Morphology Microcytic RBC: Pyridoxine deficiency, Thalassemia, Iron deficiency anemia, Chronic disease anemia (sometimes),
Red Blood Cell ( ... disease, McLeod blood ... Burr Cell RBC (Echinocyte ... Bite Cell RBC: G6PD ... differential #diagnosis #hematology
Red Blood Cell (RBC) Morphology Atlas • Microcytic - Iron-deficiency anemia, Thalassemia, Sideroblastic anemia, Lead poisoning
Red Blood Cell ( ... RBC) Morphology ... Liver diseases, Bleeding ... coagulopathy (DIC) #RBC ... #differential #hematology
Aplastic Anemia - Overview Who? • M = F • 3 peaks: 1) Childhood 2) 15-25 years 3) >60 years What? • Aplastic anemia
Aplastic Anemia ... • Aplastic anemia ... result from low blood ... #Anemia #oncology ... #hematology #diagnosis
Reticulocyte Production Index = (Retic %) x (Hct / 45) / Maturation Factor The maturation factor is
transform into a RBC ... marrow failure: Aplastic ... , Intrinsic RBC ... anemia, G6PD deficiency ... Production #Index #hematology
Leukemias Overview: ALL, CML, AML, APML, CLL Acute leukemias > 20% blasts in the peripheral blood smear
the peripheral blood ... Blast cells - Blood ... - infiltrates (anemia ... #Leukemia #Hematology ... #Oncology #Diagnosis
Chronic Lymphocytic Leukemia - Summary Cancer affecting lymphocytes/Mature B cell neoplasm • Lymphocytes accumulate in large numbers
Lymphocytosis: Absolute blood ... • Neutropenia, anemia ... aplasia • ITP ... diagnosis #workup #oncology ... #hematology
Myelodysplastic Syndromes (MDS) What? Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
cell count (anemia ... are caused by bleeding ... • Aplastic Anemia ... Syndromes #diagnosis #hematology ... #oncology
Causes of Thrombocytopenia and Platelet Disorders - Differential Diagnosis and Workup History: - Prior platelet count, family
- History of bleeding ... plateletcount), peripheral blood ... changes), high MCV anemia ... not required in all ... Causes #Workup #hematology
Blood Product Transfusions One Pager Summary Type and screen - determines blood type and detects in recipient
• Washed RBC ... recipients w/ IgA deficiency ... due to marrow aplasia ... coagulopathy & ↑bleeding ... diagnosis #management #hematology
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