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diagnosis management differential anemia product reactions aplastic atlas bruising cirrhosis coagulation cryofibrinogenemia disseminated hemostasis intravascular key leukemia mds morphology myelodysplasia
Disseminated Intravascular Coagulation (DIC) Overview Increased Clotting and Consumption of Clotting Factors Findings: • Bleeding • Recent history
ABO incompatible blood ... thrombopoietin deficiency ... Treat primary cause ... Coagulation #diagnosis #causes ... treatment #management #hematology
Red Blood Cell (RBC) Morphology Atlas • Microcytic - Iron-deficiency anemia, Thalassemia, Sideroblastic anemia, Lead poisoning
Red Blood Cell ( ... Microcytic - Iron-deficiency ... Liver diseases, Bleeding ... coagulopathy (DIC ... #differential #hematology
Bleeding and Bruising - Disorders of Hemostasis - Differential Diagnosis Framework == Quantitative or Qualitative defect in
Bleeding and Bruising ... Warfarin • Acute DIC ... discern these causes ... disease • Acute DIC ... Differential #Diagnosis #Hematology
Leukemias Overview: ALL, CML, AML, APML, CLL Acute leukemias > 20% blasts in the peripheral blood smear
the peripheral blood ... -> AML: Blast crises ... Fibrinolysis & DIC ... #Leukemia #Hematology ... #Oncology #Diagnosis
Myelodysplastic Syndromes (MDS) What? Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
by bleeding (petechiae ... or folic acid deficiency ... treatments • Copper deficiency ... Syndromes #diagnosis #hematology ... #oncology
Causes of Anemia in Cirrhosis - Differential Diagnosis Framework LOW RETIC INDEX - ↓ PRODUCTION • Vitamin
Causes of Anemia ... , Folate deficiency ... RETIC INDEX: • Blood ... Wilson's disease, DIC-low ... Differential #Diagnosis #Hepatology
Aplastic Anemia - Overview Who? • M = F • 3 peaks: 1) Childhood 2) 15-25 years 3) >60 years What? • Aplastic anemia
ecchymoses, mucosal bleeding ... and petechiae Causes ... result from low blood ... Aplastic #Anemia #oncology ... #hematology #diagnosis
Blood Transfusion Reactions Immune Mediated: • Febrile Non-Hemolytic Transfusion Reaction (FNHTR): Most common immune reaction to transfusion.
pain, dark urine, DIC ... recipients w/ IgA deficiency ... Causes purpura & ... coagulopathy & ↑bleeding ... diagnosis #management #hematology
Blood Product Transfusions One Pager Summary Type and screen - determines blood type and detects in recipient
pain, dark urine, DIC ... recipients w/ IgA deficiency ... Causes purpura & ... coagulopathy & ↑bleeding ... diagnosis #management #hematology
Cryofibrinogenemia Summary Cryofibrinogenemia Epidemiology: • 40-70 years with a modest female predominance Cryofibrinogenemia: • The precipitation of a
which can plug blood ... Paradoxical spontaneous bleeding ... cryoglobulins • Negative causes ... skin necrosis • DIC ... #hematology
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