12 results
Approach to Joint Pain - Diagnostic Framework

1) Chronicity
2) Inflammatory vs Non-Inflammatory
3) Number of Joints Involved

1) Chronicity:
Pain - Diagnostic ... Like in this case ... get bacterial seeding ... #Joint #Pain #MSK ... #rheumatology #
Causes of Knee Effusions - Differential Diagnosis Framework

Knee Effusion Red Flags:
1. Fever/Chills/Joint pain/Night sweats/Weight loss
	- DDX:
		-
Causes of Knee Effusions ... - Differential Diagnosis ... Fever/Chills/Joint ... - DDX: - Infection ... #msk #physicalexam
Top 10 situations when to think about lupus
1) Inflammatory joint pain (especially in the wrists and
) Inflammatory joint ... many differential diagnoses ... 3) Limb oedema leading ... Unexplained fever, when infection ... erythematosus #rheumatology
Hepatic Encephalopathy - Diagnosis and Management Summary
Definition:
 • Alteration in brain function manifested by neuropsychiatric symptoms
and Management ... rule out other causes ... , GI bleeding, Diuretic ... Encephalopathy #Grading ... #hepatology
Leukemias Overview: ALL, CML, AML, APML, CLL

Acute leukemias > 20% blasts in the peripheral blood smear
on bone marrow leading ... -> AML: Blast crises ... bone pain, fever, joint ... #Leukemia #Hematology ... #Oncology #Diagnosis
CNS Manifestations of Systemic Lupus Erythematosus (SLE)

Clinical Manifestations: Demyelinating Syndrome, Headache, Movement disorders, Seizure disorders, Aseptic
autoantibodies that will cause ... inflammation, leading ... permeability Diagnosis ... Lupus Cerebritis Induction ... #management #treatment
Macrophage Activation Syndrome (MAS)
Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH)

What?
A subset of
IL-1 and IL-6, leading ... purpura to mucosal bleeding ... Liver function tests ... Activation #Syndrome #Diagnosis ... #Management #Hematology
Blood Transfusion Reactions

Immune Mediated:
 • Febrile Non-Hemolytic Transfusion Reaction (FNHTR): Most common immune reaction to transfusion.
recipient antibodies leading ... Injury (TRALI): Leading ... coagulopathy & ↑bleeding ... #Transfusion #diagnosis ... #management #hematology
Blood Product Transfusions One Pager Summary
Type and screen - determines blood type and detects in recipient
indirect Coombs test ... recipient antibodies leading ... Injury (TRALI): Leading ... coagulopathy & ↑bleeding ... #management #hematology
Pulmonary Renal Syndromes - OnePager Summary
Autoimmune ANCA vasculitis (AAV): GPA (granulomatous with polyangiitis), EGPA (eosinophilic granulomatosis
anti-GBM) Other tests ... confirm DAH, r/o infection ... Goodpasture's cause ... pulmonary capillaritis leading ... #management #treatment