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diagnosis nephrology hyponatremia algorithm cancer causes emergencies gitelman hypotonic management oncologic pathophysiology physiologic table
Oncologic Emergencies - Differential Diagnosis Framework HEMATOLOGIC ONCOLOGIC EMERGENCIES: Hyperviscosity Syndrome: • Spontaneous bleeding • Shortness of breath
- Differential ... • Spontaneous bleeding ... of breath • Neurologic ... Vomiting, decreased urine ... #differential #
Causes of Hyponatremia - Differential Diagnosis Algorithm Syndrome of Inappropriate ADH - Euvolemic; no physiologic stimulus to
Hyponatremia - Differential ... Malignancy True hypovolemia ... • Bleeding ... Hypo-osmolar urine ... #Differential #
Causes of Hyponatremia - Differential Diagnosis Algorithm Syndrome of Inappropriate ADH - Euvolemic; no physiologic stimulus to
Hyponatremia - Differential ... Malignancy True hypovolemia ... • Bleeding ... Hypo-osmolar urine ... #Differential #
Gitelman Syndrome Overview What? • Inherited (AR) hypokalemic salt-losing tubulopathies affecting the thiazide-sensitive sodium chloride cotransporter • Gitelman's syndrome
thiazide-sensitive sodium ... thiazide-sensitive sodium ... Hypocalciuria (spot urine ... ratio 0.5%) Differential ... #diagnosis #nephrology
Physiologic Approach to Hypotonic Hyponatremia The next time you have a case of hypotonic hyponatremia, give the
volume-based algorithm Urine ... Present (Uosm ≥100): Hypovolemia ... Cirrhosis, Nephrotic syndrome ... #Hyponatremia #differential ... #nephrology
Hyponatremia Differential Diagnosis Algorithm in Cancer UOsm ≥ 100 mOsm/kg = Urine is inappropriately concentrated for hypotonic
Hyponatremia Differential ... 100 mOsm/kg = Urine ... appropriate • Hypovolemia ... capillary leak syndrome ... #oncology
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