16 results
Von Willebrand Disease - Most common inherited bleeding disorder 
Clinical 
 • Easy bruising 
 •
common inherited bleeding ... disorder Clinical ... • Prolonged bleeding ... factor VIII) Treatment ... Disease #Diagnosis #Hematology
Bleeding risk calculators - HAS-BLED (atrial fibrillation) and IMPROVE (VTE prophylaxis for inpatients)
Important notes:
 • No
Bleeding risk calculators ... validated for VTE treatment ... studies suggest net clinical ... with very high bleeding ... Anticoagulation #Factors #Hematology
Esophageal Variceal Bleeding - Diagnosis and Management Summary
PRE-ENDOSCOPY
Vasoactive agents - Octreotide: 
 • 50mcg bolus →
Esophageal Variceal Bleeding ... variceal ligation - EGD ... Surveillance EGD ... Diagnosis #Management #treatment ... endoscopy #varices #hepatology
Disseminated Intravascular Coagulation (DIC) Overview

Increased Clotting and Consumption of Clotting Factors

Findings:
 • Bleeding
 • Recent history
Fibrinolysis → End ... organ damage Clinical ... Treatment: ... diagnosis #causes #treatment ... #management #hematology
Acute-on-Chronic Liver Failure (ACLF) Clinical Guidelines

ACLF = possibly reversible condition in those with CLD (± cirrhosis)
Failure (ACLF) Clinical ... months without treatment ... Failure #Cirrhosis #Hepatology ... #gastroenterology
Macrophage Activation Syndrome (MAS)
Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH)

What?
A subset of
fever syndromes Clinical ... Fever is the main clinical ... purpura to mucosal bleeding ... Treatment: • Corticosteroids ... Diagnosis #Management #Hematology
Preventing Decompensation in Cirrhosis 

cACLD, CSPH, and the Rule of Five
Prevention of Decompensation
Nonselective Beta Blockers (NSBB)
Preventing
Preventing recurrent bleeding ... Cirrhosis #Prevention #treatment ... #management #hepatology ... #gastroenterology
Autoimmune Hepatitis

Clinical Presentation
 - Highly variable clinical presentation, from subclinical disease to acute liver failure.
 -
Autoimmune Hepatitis Clinical ... Highly variable clinical ... mild laboratory, clinical ... regarding need for treatment ... Diagnosis #Management #Hepatology
Hodgkin's Lymphoma vs Non-Hodgkin's Lymphoma - Comparison

Hodgkin's Lymphoma:
 • Epidemiology: young adults 20-30, older 50-70
 •
Autoimmune diseases • Clinical ... Hepatosplenomegaly, cytopenias(bleeding ... Lymphomas • Other hematologic ... Malignancies (eg ... #differential #hematology
Systemic Therapy for Hepatocellular Carcinoma - AGA Clinical Practice Guideline

First Line Treatment for HCC with Preserved
Carcinoma - AGA Clinical ... First Line Treatment ... Function Second Line Treatment ... #Management #Hepatology ... #Gastroenterology