12 results
Beta-Blockers in Cirrhosis
 • Pathophysiology
 • Indications:  Prevention of decompensation, Prevention of first variceal bleeding,
Beta-Blockers in Cirrhosis ... first variceal bleeding ... #BetaBlockers #Cirrhosis ... #hepatology #management ... #pharmacology #
Disorders of the Hepatic and Mesenteric Circulation

Platelets in Cirrhosis
Hypercoagulability in Cirrhosis
Bleeding in Cirrhosis
Portal Vein Thrombosis (PVT)
Mesenteric
Platelets in Cirrhosis ... Hypercoagulability in Cirrhosis ... Bleeding in Cirrhosis ... Circulation #Disorders #Hepatology ... #Gastroenterology
Acute-on-Chronic Liver Failure (ACLF) Clinical Guidelines

ACLF = possibly reversible condition in those with CLD (± cirrhosis)
those with CLD (± cirrhosis ... months without treatment ... Liver #Failure #Cirrhosis ... #Hepatology #gastroenterology
Preventing Decompensation in Cirrhosis 

cACLD, CSPH, and the Rule of Five
Prevention of Decompensation
Nonselective Beta Blockers (NSBB)
Preventing
Decompensation in Cirrhosis ... Preventing recurrent bleeding ... #Prevention #treatment ... #management #hepatology ... #gastroenterology
Managing warfarin INR

Warfarin dosage must be individualized according to the patient's response to the drug, and
lead to severe bleeding ... management #algorithm #pharmacology ... #treatment #medications ... decisionaid #cardiology #hematology
Diuretics and Agents Regulating Renal Excretion

Carbonic Anhydrase Inhibitors (Acetazolamide, Dichlorphenamide)
 • Glaucoma
 • Epilepsy
 • Altitude
failure, liver cirrhosis ... roentgenography • Bleeding ... with specific bleeding ... Tolvaptan) • Treatment ... Diuresis #Nephrology #Pharmacology
(DOAC interactions) Cancer-treatment specific inducers (↑) and inhibitors (↓)
of cytochrome p450 CYP3A4 and P-glycoprotein.

DOACs are substrates
interactions) Cancer-treatment ... DOACs thereby leading ... metabolization leading ... Chemotherapy #Oncology #Hematology ... Interactions #Table #Pharmacology
Checklist for Treatment of Delirium in the ICU 

Remove causative factors 
 - 
Exclude hypoglycemia if
Checklist for Treatment ... Q8hr - If cirrhotic ... consider empiric treatment ... If difficulty sleeping ... , administer pharmacologic
Hepatic Encephalopathy - Diagnosis and Management Summary
Definition:
 • Alteration in brain function manifested by neuropsychiatric symptoms
Prevalence: At cirrhosis ... Infection, GI bleeding ... noxious stimuli) TREATMENT ... Initiate empiric treatment ... #hepatology
Systemic Therapy for Hepatocellular Carcinoma - AGA Clinical Practice Guideline

First Line Treatment for HCC with Preserved
First Line Treatment ... Function Second Line Treatment ... #Management #Hepatology ... #Gastroenterology ... #oncology #Pharmacology