18 results
Beta-Blockers in Cirrhosis
 • Pathophysiology
 • Indications:  Prevention of decompensation, Prevention of first variceal bleeding,
Beta-Blockers in Cirrhosis ... first variceal bleeding ... #BetaBlockers #Cirrhosis ... #hepatology #management ... #pharmacology #
Disorders of the Hepatic and Mesenteric Circulation

Platelets in Cirrhosis
Hypercoagulability in Cirrhosis
Bleeding in Cirrhosis
Portal Vein Thrombosis (PVT)
Mesenteric
Platelets in Cirrhosis ... Hypercoagulability in Cirrhosis ... Bleeding in Cirrhosis ... Circulation #Disorders #Hepatology ... #Gastroenterology
Here is a quick guide on the common direct-acting antivirals (DAAs) for chronic hepatitis C virus
DAAs #Antivirals #table ... #treatment #hcv ... infectiousdisease #hepatology ... HepatitisC #Management #Pharmacology
Managing warfarin INR

Warfarin dosage must be individualized according to the patient's response to the drug, and
lead to severe bleeding ... management #algorithm #pharmacology ... #treatment #medications ... #table #pharmacotherapy ... decisionaid #cardiology #hematology
Acute-on-Chronic Liver Failure (ACLF) Clinical Guidelines

ACLF = possibly reversible condition in those with CLD (± cirrhosis)
those with CLD (± cirrhosis ... months without treatment ... Liver #Failure #Cirrhosis ... #Hepatology #gastroenterology
Preventing Decompensation in Cirrhosis 

cACLD, CSPH, and the Rule of Five
Prevention of Decompensation
Nonselective Beta Blockers (NSBB)
Preventing
Decompensation in Cirrhosis ... Preventing recurrent bleeding ... #Prevention #treatment ... #management #hepatology ... #gastroenterology
Diuretics and Agents Regulating Renal Excretion

Carbonic Anhydrase Inhibitors (Acetazolamide, Dichlorphenamide)
 • Glaucoma
 • Epilepsy
 • Altitude
roentgenography • Bleeding ... with specific bleeding ... Tolvaptan) • Treatment ... Diuresis #Nephrology #Pharmacology ... #Medications #Table
(DOAC interactions) Cancer-treatment specific inducers (↑) and inhibitors (↓)
of cytochrome p450 CYP3A4 and P-glycoprotein.

DOACs are substrates
interactions) Cancer-treatment ... DOACs thereby leading ... Chemotherapy #Oncology #Hematology ... #Interactions #Table ... #Pharmacology
Perioperative Management of DOACs
Problem:
 ✖ Each year approximately 250,000 patients on chronic anticoagulation in North America
interruption per treatment ... table ... and procedural bleeding ... with a very low bleeding ... #pharmacology #
Checklist for Treatment of Delirium in the ICU 

Remove causative factors 
 - 
Exclude hypoglycemia if
Checklist for Treatment ... Q8hr - If cirrhotic ... consider empiric treatment ... If difficulty sleeping ... , administer pharmacologic