76 results
Causes of Hematuria - Differential Diagnosis Algorithm
Red blood cells on urine microscopy. Must exclude false positives
Causes of Hematuria ... blood cells on urine ... Tubulolnterstitial • Calculi ... • BPH • Calculi ... RBCs and/or RBC casts
Causes of Hematuria - Differential Diagnosis
Renal:
 - Glomerular - IgA Nephropathy, Thin basement membrane, Alport syndrome,
Causes of Hematuria ... or other tumor, Calculi ... - Structural - Cysts ... - Malignancy, Calculi ... Schistomiasis, Malignancy, Calculi
Algorithm and Differential Diagnosis of Macroscopic Hematuria
Important Historical Elements:
- Painless: suggests malignancy
- Painful: suggests calculi/infection
- Urinalysis:
of Macroscopic Hematuria ... Painful: suggests calculi ... RBC’s, RBC/WBC casts ... #IM #Urology #Hematuria
Urine Microscopy and Casts - Image Atlas Key

- Squamous Epithelial Casts
- Transitional Epithelial Cells
- Renal Tubular
Urine Microscopy ... and Casts - Image ... - WBC Cast - ... Cast - Waxy Cast ... JoseTesser) #Urine
Nephritic vs Nephrotic Syndrome

Step 1: If the patient has hematuria and/or proteinuria, think about nephrotic/nephritic syndromes.
Step
the patient has hematuria ... have glomerular hematuria ... (RBC casts or dysmorphic ... RBCs in urine)?
Hematuria - Differential Diagnosis Framework

Gross Hematuria: Red/Dark urine
 • 1ml blood/liter urine can induce color change
: Red/Dark urine ... 1ml blood/liter urine ... more RBC/HPF spun urine ... examination of urine ... : - RBC casts
Hematuria Workup and Diagnosis Algorithm
 • Confirm hematuria → Urinalysis >3 RBCs/HPF, exclude mimics, repeat testing
Hematuria Workup ... Algorithm • Confirm hematuria ... WBCs, or urine ... proteinuria, RBC casts ... uw_IMresidency #Hematuria
Granular & “Muddy Brown” Casts on Urine Microscopy
A. Finely granular cast B. slightly coarser granular cast
“Muddy Brown” Casts ... on Urine Microscopy ... Finely granular cast ... “urine poker quads ... #Urine #Microscopy
Mixed Cellular Casts on Urine Microscopy

Degenerating mixed cellular cast - brightfield, unstained - from patient with
Mixed Cellular Casts ... on Urine Microscopy ... mixed cellular cast ... #Cellular #Casts ... #clinical #Urine
Glomerular Diseases - Nephritic and Nephrotic Syndromes

Nephritic syndrome—due to GBM disruption. 
Hypertension. t BUN and creatinine.
hematuria. ... RBC casts in urine ... but in severe cases