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diagnosis hematology management thrombocytosis chronic classification dermatology hodgkins ibd iron lymphoma mds myelodysplasia myelodysplastic nonpalpable nutrition palpable platelet platelets purpura
Hemolytic Anemia - Differential Diagnosis Algorithm • Sickle cells - Consider sickle cell disease (diverse genotypes):
Hemolytic Anemia ... - Differential ... Consider RBC membrane disorder ... #Anemia #Differential ... #workup #hematology
Causes of Thrombocytosis - Differential Diagnosis Algorithm Spurious: • Artifact (redo CBC) Autonomous: • Essential thrombocytosis • Polycythemia
- Differential ... • Rheumatic disorders ... • Celiac disease ... malignancy • Iron deficiency ... anemia #Thrombocytosis
Causes of Iron Deficiency • Diet: ↓ Intake, e.g. vegan, Malnutrition, Polyphenol / tannins, ↓ Vitamin
Causes of Iron Deficiency ... , Chronic disease ... Iron metabolism disorders ... #Causes #differential ... #diagnosis #anemia
Fatigue and IBD Algorithm • 40-50% patients have fatigue despite clinical remission • Risk factors: BMI,
Fatigue and IBD ... restricted diet/deficiency ... despite disease ... /other causes • ... #IBD #Algorithm
Causes of Fatigue - Differential Diagnosis Algorithm Endocrine • Hypo/Hyperthyroidism • Diabetes • Pituitary Insufficiency • Adrenal
Causes of Fatigue ... Hematologic • Anemia ... Obstructive Pulmonary Disease ... Neurologic • ... • Somatization Disorder
Causes of Thrombocytopenia and Platelet Disorders - Differential Diagnosis and Workup History: - Prior platelet count, family
- Differential ... Diagnosis and Workup ... (CVID, WAS), (neurologic ... changes), high MCV anemia ... #Differential #
Purpura - Differential Diagnosis Framework Non-blanchable, dark red to purple, hemorrhagic skin lesions that result from leakage
Purpura - Differential ... DIC/TTP/HUS - Hemolytic ... anemia - Splenomegaly ... necrosis) • VIT K deficiency ... Vasculopathy #Purpura #Differential
Approach to Thrombocytosis - Elevated Platelet Count - Differential Diagnosis Algorithm Peripheral Smear concerning for malignancy?
hematology for workup ... blood loss, Acute hemolysis ... , deficiency anemia ... Vasculitides, IBD ... , Celiac disease
Myelodysplastic Syndromes (MDS) What? Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
formed or don’t work ... Symptoms: • Fatigue ... Myeloproliferative Disease ... blood count with differential ... diagnosis #hematology #oncology
Hodgkin's Lymphoma Overview Hodgkin's lymphoma (HL) is an uncommon hematological malignancy arising from mature B cells. It
• Autoimmune disorders ... nodosum • Immune hemolytic ... Hodgkin Lymphoma Workup ... number of sites of disease ... classification #hematology #oncology
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