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systemic pruritus thrombocytosis cold elevatedmcv extravascular ferritin hemolysis intravascular iron macrocytic macrocytosis myelodysplasia naildisorders nonpalpable palpable platelets primary purpura rheumatology
Causes of Thrombocytosis - Differential Diagnosis Secondary Thrombocytosis (a.k.a Reactive Thrombocytosis): • Acute infection • Solid organ
Diagnosis Secondary ... malignancies • Anemia ... syndrome • Myelofibrosis ... #Diagnosis #Causes ... #hematology #secondary
Cold Agglutinin Disease 3 Types of Cold Sensitive Antibodies: 1. Cold Agglutinins (CAD) 2. Donath-Landsteiner
Disease (CAD): ... Agglutinin Syndrome ... Diagnosis: • hemolytic ... #disease #hemolytic ... #anemia #hematology
Diagnostic Framework for Hemolysis - Intravascular vs Extravascular Causes Intravascular Hemolysis: • Mechanical Trauma (Microangiopathic hemolytic anemia):
) - HELLP syndrome ... uremic syndrome ... G6PD deficiency) ... #differential # ... diagnosis #hematology
Pruritus - Generalized Differential Diagnosis Algorithm - Systemic and Primary Causes == Primary Skin Lesions == Macules /
Differential Diagnosis ... syndrome Psychiatric ... Pruritus #primary #secondary ... #dermatology #Differential ... #Diagnosis #Algorithm
Causes of Anemia with elevated Mean Corpuscular Volume (MCV) - Differential Diagnosis Algorithm Normal Blood Smear •
Causes of Anemia ... Diagnosis Algorithm ... Syndromes Macrocytosis ... #Diagnosis #Algorithm ... #Causes #Hematology
Purpura - Differential Diagnosis Framework Non-blanchable, dark red to purple, hemorrhagic skin lesions that result from leakage
anemia - Splenomegaly ... Kasabach-Merritt syndrome ... Gardner-Diamond syndrome ... #Diagnosis #hematology ... #nonpalpable #dermatology
Pruritus - No Primary Skin Lesion - Differential Diagnosis Algorithm Blood Glucose: • Diabetes Mellitus Liver Function Tests/Enzymes:
Diagnosis Algorithm ... syndrome Psychiatric ... #dermatology #Differential ... #Diagnosis #Algorithm ... #causes
Myelodysplastic Syndromes (MDS) What? Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
Syndromes (MDS) ... DDX: Rule Out Secondary ... Causes • Anemia ... #Syndromes #diagnosis ... #hematology #oncology
Iron Deficiency Anemia - Differential Diagnosis Algorithm Labs: Ferritin, iron, transferrin, TIBC, TSAT, sTfR • Blood loss:
Anemia - Differential ... Diagnosis Algorithm ... Gastrectomy, WHDA syndrome ... #Anemia #Differential ... #ferritin #hematology
Approach to Thrombocytosis - Elevated Platelet Count - Differential Diagnosis Algorithm Peripheral Smear concerning for malignancy?
Diagnosis Algorithm ... , deficiency anemia ... Kawasaki, Nephrotic syndrome ... #Diagnosis #Algorithm ... #hematology
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