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systemic generalized secondary thrombocytosis classification cll erythematosus gap hemodialysis hodgkins lupus lymphocytic lymphoma mds monoclonal myelodysplasia myelodysplastic paraproteinemias platelets primary
Causes of Thrombocytosis - Differential Diagnosis Algorithm Spurious: • Artifact (redo CBC) Autonomous: • Essential thrombocytosis • Polycythemia
Diagnosis Algorithm ... Myelogenous Leukemia ... Iron deficiency anemia ... #Diagnosis #Algorithm ... #Causes #Hematology
Pruritus - Generalized Differential Diagnosis Algorithm - Systemic and Primary Causes == Primary Skin Lesions == Macules /
Differential Diagnosis ... renal failure/uremia ... • Lymphoma • Leukemia ... #generalized #dermatology ... Diagnosis #Algorithm
Pruritus - No Primary Skin Lesion - Differential Diagnosis Algorithm Blood Glucose: • Diabetes Mellitus Liver Function Tests/Enzymes:
Diagnosis Algorithm ... renal failure/uremia ... #generalized #dermatology ... Diagnosis #Algorithm ... #causes
Approach to Thrombocytosis - Elevated Platelet Count - Differential Diagnosis Algorithm Peripheral Smear concerning for malignancy?
Thrombocytosis - Elevated ... Diagnosis Algorithm ... → Refer to hematology ... #Diagnosis #Algorithm ... #hematology
Chronic Lymphocytic Leukemia - Summary Cancer affecting lymphocytes/Mature B cell neoplasm • Lymphocytes accumulate in large numbers
cells can indicate disease ... • Neutropenia, anemia ... increase in gamma globulins ... #diagnosis #workup ... #oncology #hematology
Elevated Globulin - Protein Gap (Total Protein - Albumin > 4) Work-up of an Elevated Globulin Gap: •
Elevated Globulin ... Albumin > 4) Work-up ... An elevated globulin ... gastric tumors • Hematology ... #diagnosis #hematology
Management of Pruritus in Patients with Chronic Kidney Disease Pruritus with no primary lesions - differential diagnosis:
Management of Pruritus ... diagnosis: • ... Renal pruritus ... #Management #Nephrology ... #CKD
Paraproteinemias Entities That Can Feature A Monoclonal Protein/M Component: • MM • WM • MGUS • MGCS • MGRS • Splenic Marginal Zone
Autoantibodies: • WAIHA • CAD ... (-) hemolytic anemia ... vascular beds-renal ... Paraproteinemias #Hematology ... #Diagnosis #Oncology
SLE (Systemic Lupus Erythematosus) Suspect: Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
sediment, and elevated ... Valvular disorders • CAD ... APLA/LAC: • Renal ... with Lupus: • Chronic ... #Rheumatology
Hodgkin's Lymphoma Overview Hodgkin's lymphoma (HL) is an uncommon hematological malignancy arising from mature B cells. It
• Pruritis ... Hodgkin Lymphoma Workup ... number of sites of disease ... classification #hematology ... #oncology #management
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