cbd disease differential algorithm workup hematology nephrology pulmonary anemia hypertension primary dyspnea disorders pancytopenia

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Pancytopenia - Workup and Differential Diagnosis Algorithm
Consumption Disorders
1. Autoimmune Mediated Pancytopenia
2. Splenic Sequestration
Peripheral Destruction

Pancytopenia - Workup ... Primary hematological ... Metastatic Disease ... #Workup #Differential ... #Hematology

Causes of Thrombocytosis - Differential Diagnosis Algorithm
Spurious:
• Artifact (redo CBC)
Autonomous:
• Essential thrombocytosis
• Polycythemia

Diagnosis Algorithm ... Myelogenous Leukemia • Primary ... • Rheumatic disorders ... • Celiac disease ... Iron deficiency anemia

Causes of Thrombocytopenia and Platelet Disorders - Differential Diagnosis and Workup
History:
- Prior platelet count, family

- Differential ... changes), high MCV anemia ... unclear, or if a primary ... hematologic disorder ... ITP, unexplained pancytopenia

Hemolytic Anemia - Differential Diagnosis Algorithm
• Sickle cells - Consider sickle cell disease (diverse genotypes):

Hemolytic Anemia ... - Differential ... vasculitis, malignant hypertension ... Consider RBC membrane disorder ... #workup #hematology

Cold Agglutinin Disease

3 Types of Cold Sensitive Antibodies:
1. Cold Agglutinins (CAD)
2. Donath-Landsteiner

15% of AIHA Primary ... • Symptoms of anemia ... fatigue, pallor, dyspnea ... younger pts) Differential ... #hematology #diagnosis

SLE (Systemic Lupus Erythematosus)

Suspect:
Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and

permanent alopecia Differential ... Malignancy (e.g. hematologic ... the context of primary ... Frank nephritis (hypertension ... lymphopenia, low PLT • Anemia

Management of Pruritus in Patients with Chronic Kidney Disease
Pruritus with no primary lesions - differential diagnosis:

Pruritus with no primary ... lesions - differential ... pruritus • Hematologic ... Iron deficiency anemia ... #Management #Nephrology

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