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On the left three different patients with lung cysts.
From left to right: Lymphangiomyomatosis, LIP and Langerhans
and Langerhans cell ... #Clinical #Diagnosis ... Histiocytosis #RadiologyAssistant
Differential diagnosis of Langerhans cell histiocytosis.
Nodular LCH:
- Sarcoidosis: perilymphatic distribution.
- Metastases: random distribution.
Cystic LCH:
- LAM: round
Differential diagnosis ... of Langerhans cell ... central dot. - LIP #Clinical ... #Diagnosis #Radiology ... Comparison #Table #RadiologyAssistant
Upper lung zone preference is seen in:
- Inhaled particles: pneumoconiosis (silica or coal)
- Smoking related diseases
) - Langerhans cell ... Pulmonary edema #Diagnosis ... #Upper #Lower #RadiologyAssistant
The fourth pattern includes abnormalities that result in decreased lung attenuation or air-filled lesions.
These include:
- Emphysema
-
LIP, Langerhans cell ... #Diagnosis #Radiology ... Emphysema #SignetRing #RadiologyAssistant
Chronic Lymphocytic Leukemia - Summary

Cancer affecting lymphocytes/Mature B cell neoplasm
 • Lymphocytes accumulate in large numbers
lymphocytes/Mature B cell ... Orange or Hep C Clinical ... phenomenon CLL Diagnosis ... or basket cells ... Lymphocytic #Leukemia #diagnosis
Acute Rheumatic Fever: Pathogenesis and Clinical Findings

Delayed autoimmune reaction
-> Molecular mimicry
-> GAS antigen cross-reacts with host
->
Pathogenesis and Clinical ... B and CD-4+ T cells ... CRP Neuronal cell ... surface targeted -> Cell ... pathophysiology #diagnosis
Hodgkin's Lymphoma vs Non-Hodgkin's Lymphoma - Comparison

Hodgkin's Lymphoma:
 • Epidemiology: young adults 20-30, older 50-70
 •
typically of B-cell ... Autoimmune diseases • Clinical ... Noncontiguous spread • Clinical ... Differential Diagnosis ... comparison #oncology #diagnosis
Retinoblastoma: Pathogenesis and clinical findings
 • Sporadic mutation -> One allele of RB1 tumor suppressor gene
Pathogenesis and clinical ... mutated in one cell ... transformation of the cell ... mutated in all cells ... ophthalmology #diagnosis
Consolidation is synonymous with airspace disease.
When you think of the causes of consolidation, think of 'what
blood or tumor cells ... #Diagnosis #Radiology ... #Differential #RadiologyAssistant
Nodular pattern(2)
1. Sarcoidosis: nodules with perilymphatic distribution, along fissures, adenopathy.
2. TB: Tree-in-bud appearance in a patient
Langerhans cell ... #Clinical #Radiology ... Comparison #Table #RadiologyAssistant