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differential injury hematology transaminitis acute biliary cholangitis cirrhosis common cvid diffuse dili druginduced elevated gap globulin hepatocellular hepatomegaly hypogammaglobulinemia immunodeficiency
Causes of Acute Liver Injury - Differential Diagnosis Hepatocellular - Liver Parenchyma • Infectious: Hepatitis C, A,
Causes of Acute ... Diagnosis Hepatocellular ... • Infectious: ... E, B, D, EBV, CMV ... #algorithm #hepatology
Hepatomegaly - Differential Diagnosis Algorithm Malignant • Primary Carcinoma • Metastases • Lymphoma • Leukemia • Polycythemia
Algorithm Malignant ... Non-Malignant • Fatty Liver ... Pericarditis Infectious ... #Algorithm #Causes ... #Hepatology
Elevated Transaminases / Transaminitis - Differential Diagnosis • Infectious: HAV, HCV, HEV, EBV, HSV, CMV •
- Differential Diagnosis ... • Infectious ... HAV, HCV, HEV, EBV ... Trauma: Shock liver ... #causes #hepatology
Drug Induced Liver Injury (DILI) - Stepwise Diagnosis Algorithm DILI suspicion Features toxic aetiology: Skin involvement, Kidney injury,
Algorithm DILI ... for alternative causes ... Hepatocellular: Viral infections ... HBV, HCV, HEV, EBV ... #Algorithm #hepatology
Causes of Diffuse Lymphadenopathy - Differential Diagnosis Algorithm Reactive: - Systemic Inflammatory •
Causes of Diffuse ... Algorithm Reactive ... • EBV ... Tuberculosis • Hepatitis ... #Algorithm #Causes
Hepatocellular Liver Injury - Differential Diagnosis Framework: Liver Injury → liver test abnormalities without evidence of liver
: • Infections ... : Hepatitis A/B/ ... C/D/E, EBV, CMV, ... #hepatology #algorithm ... Transaminitis #LFTs #hepatitis
Acute Liver Injury - Differential Diagnosis Algorithm Vascular Causes of Acute Liver Injury: • Hepatic vein:
- Differential Diagnosis ... Algorithm Vascular ... Causes of Acute ... Injury: • Infectious ... #algorithm #hepatology
Primary Biliary Cirrhosis (PBC) - Summary PBC Epidemiology: • Female:Male 9:1 • Common European descent • Age:
intralobular bile ducts causes ... or higher • Liver ... : • Viral hepatitis ... fungal, viral infections ... #workup #hepatology
Common Variable Immunodeficiency (CVID) What? CVID: Immunodeficiency disorder with hypogammaglobulinemia -> increased infection risk secondary to impaired B-cell
late adulthood • Diagnosis ... disease • Liver ... diseases and hepatitis ... Chest CT: • Ground-glass ... DDX - Other causes
Elevated Globulin - Protein Gap (Total Protein - Albumin > 4) Work-up of an Elevated Globulin Gap: •
Include: • Viral infections ... acute HIV, HBV, EBV ... , VZV, hepatitis ... Sarcoidosis) • Liver ... #differential #diagnosis
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