11 results
Drug Induced Liver Injury (DILI) - Stepwise Diagnosis Algorithm
DILI suspicion
Features toxic aetiology: Skin involvement, Kidney injury,
Stepwise Diagnosis ... Algorithm DILI ... Hepatocellular: Viral infections ... #Diagnosis #Algorithm ... #hepatology
Acute-on-Chronic Liver Failure (ACLF) Clinical Guidelines

ACLF = possibly reversible condition in those with CLD (± cirrhosis)
Coagulation Failure Infections ... Injury (DILI) ... Viral Hepatitis ... #Hepatology #gastroenterology ... #management #diagnosis
Elevated Transaminases / Transaminitis - Differential Diagnosis

 • Infectious: HAV, HCV, HEV, EBV, HSV, CMV
 •
Infectious ... HAV, HCV, HEV, EBV ... Trauma: Shock liver ... • Iatrogenic: DILI ... #causes #hepatology
Hepatomegaly - Differential Diagnosis Algorithm
Malignant
 • Primary Carcinoma
 • Metastases
 • Lymphoma
 • Leukemia
 • Polycythemia
Algorithm Malignant ... Non-Malignant • Fatty Liver ... Pericarditis Infectious ... Primary Biliary Cirrhosis ... #Hepatology
Patterns of Liver Injury
Transaminase Levels:
  > 50x normal - Ischemic Hepatitis
  > 20x normal
10-20x normal - Infection ... (EBV/CMV), Alcoholic ... cirrhosis, Portal ... #Injury #hepatology ... #differential #diagnosis
Acute Liver Injury - Differential Diagnosis Algorithm

Vascular Causes of Acute Liver Injury: 
 • Hepatic vein:
Algorithm Vascular ... Injury: • Infectious ... • Iatrogenic: DILI ... : < 1 • Cirrhosis ... #algorithm #hepatology
Chronic Hepatitis B - Diagnosis and Management Algorithm

• Who to treat: Essentially treat the pts with
B - Diagnosis and ... Management Algorithm ... viremia or have cirrhosis ... B Infection: A ... #Treatment #Hepatology
Causes of Acute Liver Injury - Differential Diagnosis
Hepatocellular - Liver Parenchyma
 • Infectious: Hepatitis C, A,
- Differential Diagnosis ... Parenchyma • Infectious ... , E, B, D, EBV, ... Causes #Acute #algorithm ... #hepatology
Hepatocellular Liver Injury - Differential Diagnosis Framework:
Liver Injury → liver test abnormalities without evidence of liver
: • Infections ... : Hepatitis A/B/ ... C/D/E, EBV, CMV, ... #hepatology #algorithm ... Transaminitis #LFTs #hepatitis
Primary Biliary Cirrhosis (PBC) - Summary

PBC Epidemiology:
 • Female:Male 9:1
 • Common European descent
 • Age:
/Liver failure ... or higher • Liver ... : • Viral hepatitis ... fungal, viral infections ... #workup #hepatology