11 results
Patterns of Liver Injury
Transaminase Levels:
  > 50x normal - Ischemic Hepatitis
  > 20x normal
10-20x normal - Infection ... cirrhosis, Portal ... #Injury #hepatology ... #LFTs #transaminitis ... #differential #diagnosis
Hepatomegaly - Differential Diagnosis Algorithm
Malignant
 • Primary Carcinoma
 • Metastases
 • Lymphoma
 • Leukemia
 • Polycythemia
Algorithm Malignant ... Non-Malignant • Fatty Liver ... Pericarditis Infectious ... Primary Biliary Cirrhosis ... #Hepatology
Hepatocellular Liver Injury - Differential Diagnosis Framework:
Liver Injury → liver test abnormalities without evidence of liver
: • Infections ... C/D/E, EBV, CMV, ... #hepatology #algorithm ... Transaminitis #LFTs ... #hepatitis
Chronic Hepatitis B - Diagnosis and Management Algorithm

• Who to treat: Essentially treat the pts with
B - Diagnosis and ... Management Algorithm ... viremia or have cirrhosis ... B Infection: A ... #Treatment #Hepatology
Elevated Liver Enzymes - Differential Diagnosis Algorithm
Severe ALT > 15x ULN
 • Viral
 • Drugs/Toxins
 •
Elevated Liver Enzymes ... • Alcoholic hepatitis ... Infiltrative • Cirrhosis ... • Others #LFTs ... #Hepatology #LiverEnzymes
Causes of Acute Liver Injury - Differential Diagnosis
Hepatocellular - Liver Parenchyma
 • Infectious: Hepatitis C, A,
- Differential Diagnosis ... Parenchyma • Infectious ... , E, B, D, EBV, ... Causes #Acute #algorithm ... #hepatology
Abnormal Liver Function Tests - Differential Diagnosis Algorithm for Transaminitis
Hepatocellular Pattern (ALT or AST > ALP):
Abnormal Liver Function ... Alcoholic Hep, Drugs, Infection ... Congenital, Others, Cirrhosis ... Burak @kwburak #LFTs ... #diagnosis #hepatology
Drug Induced Liver Injury (DILI) - Stepwise Diagnosis Algorithm
DILI suspicion
Features toxic aetiology: Skin involvement, Kidney injury,
DILI) - Stepwise Diagnosis ... Algorithm DILI ... Hepatocellular: Viral infections ... HBV, HCV, HEV, EBV ... #Algorithm #hepatology
Primary Biliary Cirrhosis (PBC) - Summary

PBC Epidemiology:
 • Female:Male 9:1
 • Common European descent
 • Age:
/Liver failure ... or higher • Liver ... : • Viral hepatitis ... fungal, viral infections ... #workup #hepatology
Acute Liver Injury - Differential Diagnosis Algorithm

Vascular Causes of Acute Liver Injury: 
 • Hepatic vein:
- Differential Diagnosis ... Algorithm Vascular ... Injury: • Infectious ... : < 1 • Cirrhosis ... #algorithm #hepatology