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differential nephrology rheumatology acute aki algorithm injury kidney pulmonary renal ana anca antibodies antibody antineutrophil antinuclear classification diseases hypertension indications
Vasculitis and Vasculitides - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions •
tract, and often causes ... - GI tract: abdominal ... < 30 years - Aorta ... branches • GCA: - Aorta ... Supply gut -> abdominal
Pulmonary Renal Syndrome Definition: Diffuse alveolar hemorrhage + Glomerulonephritis Presentation (Pulmonary and renal manifestations can occur weeks apart):
ANCA-positive vasculitis ... ANCA-negative vasculitis ... IgA-associated vasculitis ... ab, ANA, C3, C4 ... resolution chest CT
Acute Kidney Injury - AKI Workup Algorithm and Differential Diagnosis Baseline Investigations: full blood count with differential,
Kidney Injury - AKI Workup ... and Differential Diagnosis ... Glomerulonephritis / Vasculits ... : ANCA, ANA, Anti-GBM ... renal biopsy • Abdominal
Acute Kidney Injury (AKI) - Differential Diagnosis Framework Pre-Renal: • Hypovolemia, Cardiorenal, Distributive Shock, HRS, Hypercalcemia, Renal
Artery Stenosis, Abdominal ... Compartment Syndrome ... Emboli, Thrombosis, Vasculitis ... GN: ANCA, Anti-GBM ... #nephrology #causes
Pulmonary Renal Syndromes - OnePager Summary Autoimmune ANCA vasculitis (AAV): GPA (granulomatous with polyangiitis), EGPA (eosinophilic granulomatosis
Autoimmune ANCA vasculitis ... palpable purpura 2/2 vasculitis ... mononeuritis multiplex WORKUP ... Other tests: • CT ... Goodpasture's cause
Vasculitis - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions • Mononeuritis multiplex • Hematuria, proteinuria,
Diagnosis Framework ... < 30 years • Aorta ... Arteritis): • Aorta ... tract, and often causes ... gut involvement, abdominal
ANA (Antinuclear Antibody) and ANCA (Antineutrophil cytoplasmic antibodies) • Systemic lupus erythematosus 1. Anti-dsDNA
• Sjögren syndrome ... ANCA-Associated Vasculitis ... Renal-limited vasculitis ... + 90% • Anti-GBM ... Antineutrophil #antibodies #diagnosis
Causes of Secondary Hypertension - Workup and Differential Diagnosis Approach (when evaluation should be done): 1. Severe or
Hypertension - Workup ... and Differential Diagnosis ... Coarctation of aorta ... , Vasculitis • ... #Hypertension #Workup
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