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diagnosis differential hematology management classification vasculitis blurry cryofibrinogenemia hemeonc hemophagocytic hlh hodgkins lymphohistiocytosis lymphoma manifestations myopathy myositis neurology neuromyelitis nmo
Neuromyelitis Optica (NMO) - Clinical Manifestations • Optic neuritis: Reduced visual acuity, ranging from mild to
desaturation, Scotoma, Ocular ... involvement: Intractable nausea ... Myositis, Comorbid autoimmune ... disorders (Systemic ... neurology #symptoms #signs
Blurry Vision - Differential Diagnosis Framework Anatomical Approach to Eye Disease: 1. Lids/Lashes 2. Extraocular Muscles/Motility 3. Conjunctiva/Sclera 4. Cornea 5. Anterior
Anterior Chamber ... Ocular Adverse Effects ... of Systemic Medications ... • Sjögren’s syndrome ... ophthalmology #causes
Sjogren's Syndrome Overview Epidemiology: • F > M: 9:1 • 5-6th Decades (can be any age) Autoimmune exocrinopathy multisystemic disease
be any age) Autoimmune ... gland) biopsy • Ocular ... Hypocomplementemia • Can cause ... Central nervous system ... #Rheumatology #
Vasculitis and Vasculitides - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions •
tract, and often causes ... ulcers, cutaneous, ocular ... • Cogan Syndrome ... purpura: strong sign ... differential #diagnosis #rheumatology
Cryofibrinogenemia Summary Cryofibrinogenemia Epidemiology: • 40-70 years with a modest female predominance Cryofibrinogenemia: • The precipitation of a
associated with autoimmune ... processes: • Systemic ... pulmonary emboli, and ocular ... cryoglobulins • Negative causes ... Antiphospholipid syndrome
Vasculitis - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions • Mononeuritis multiplex • Hematuria, proteinuria,
purpura: Strong sign ... tract, and often causes ... ulcers, cutaneous, ocular ... : Ocular inflammatory ... Differential #Diagnosis #Rheumatology
Hodgkin's Lymphoma Overview Hodgkin's lymphoma (HL) is an uncommon hematological malignancy arising from mature B cells. It
of about three cases ... Immunosuppression • Autoimmune ... supraclavicular node • Anterior ... classification #hematology ... #oncology #management
Autoimmune Myositis - Differential Diagnosis Framework Inflammatory Myopathies: Commonly symmetric proximal muscle weakness, no substantial muscle pain
RP-ILD), dermato-rheumatologic ... papules and Gottron sign ... ) • Shawl sign ... • Conduction system ... statins - probably caused
Hemophagocytic Lymphohistiocytosis (HLH) High mortality without prompt recognition and management. HLH is a critical diagnostic consideration in
caused by uncontrolled ... of the immune system ... Malignancies ▪ Autoimmune ... Presentation • Common Signs ... Infections, malignancy, autoimmune
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