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diagnosis differential hematology management symptoms vasculitis behcet blurry classification comatose cryofibrinogenemia disease hemeonc hemophagocytic hlh lymphohistiocytosis manifestations monoclonal neuromyelitis nmo
Neuromyelitis Optica (NMO) - Clinical Manifestations • Optic neuritis: Reduced visual acuity, ranging from mild to
desaturation, Scotoma, Ocular ... involvement: Intractable nausea ... autoimmune disorders (Systemic ... Manifestations #diagnosis #neurology ... #symptoms #signs
Blurry Vision - Differential Diagnosis Framework Anatomical Approach to Eye Disease: 1. Lids/Lashes 2. Extraocular Muscles/Motility 3. Conjunctiva/Sclera 4. Cornea 5. Anterior
Anterior Chamber ... Ocular Adverse Effects ... of Systemic Medications ... • Sjögren’s syndrome ... ophthalmology #causes
Paraproteinemias Entities That Can Feature A Monoclonal Protein/M Component: • MM • WM • MGUS • MGCS • MGRS • Splenic Marginal Zone
clubbing Clarkson/Systemic ... et diutinum Neurologic ... neuropathy) • Systemic ... Hypergammaglobulinemic macular ... Paraproteinemias #Hematology
Behçet's Syndrome Systemic disease associated with inflammation of multiple organs, small-vessel vasculitis and large-vessel vasculopathy Epidemiology: • Young
Systemic disease ... ulceration • Ocular ... skin injury) • Neurologic ... diagnosis #management #signs ... #symptoms #rheumatology
Vasculitis and Vasculitides - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions •
tract, and often causes ... ulcers, cutaneous, ocular ... • Cogan Syndrome ... purpura: strong sign ... differential #diagnosis #rheumatology
Vasculitis - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions • Mononeuritis multiplex • Hematuria, proteinuria,
purpura: Strong sign ... affects the skin, neurologic ... cognitive impairment, neurologic ... tract, and often causes ... Differential #Diagnosis #Rheumatology
Cryofibrinogenemia Summary Cryofibrinogenemia Epidemiology: • 40-70 years with a modest female predominance Cryofibrinogenemia: • The precipitation of a
processes: • Systemic ... pulmonary emboli, and ocular ... cryoglobulins • Negative causes ... Antiphospholipid syndrome ... #hematology
SAPHO Syndrome Summary What? SAPHO syndrome is a rare chronic inflammatory disorder of bone, joint, and skin characterized
involvement: May involve anterior ... Rule out other causes ... sites such as the collar ... #Rheumatology # ... diagnosis #management #Dermatology
The Neurological Evaluation of a Comatose Patient Definition: • Coma: a state of unresponsiveness; the absence of
• Locked-in syndrome ... reticular activating system ... • Vestibulo-ocular ... • Examine for signs ... #PhysicalExam #neurology
Hemophagocytic Lymphohistiocytosis (HLH) High mortality without prompt recognition and management. HLH is a critical diagnostic consideration in
hyperinflammatory syndrome ... caused by uncontrolled ... of the immune system ... Presentation • Common Signs ... Diagnosis #Management #Hematology
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