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diagnosis differential lupus ophthalmology vasculitis activation approach behcet blurry causes cerebritis classification dermatology disease eyeexamination hematology macrophage mas neurology ocular
CNS Manifestations of Systemic Lupus Erythematosus (SLE) Clinical Manifestations: Demyelinating Syndrome, Headache, Movement disorders, Seizure disorders, Aseptic
CNS Manifestations ... Demyelinating Syndrome ... #SLE #CNS #neurology ... #rheumatology # ... cerebritis #diagnosis #management
Systemic Lupus Erythematosus - Summary Antinuclear (ANA) - 95% - Initial screening test Anti-dsDNA - 50% • Associated
Systemic Lupus Erythematosus ... block • Sjogren syndrome ... #Lupus #Erythematosus ... diagnosis #rheumatology ... #management
SLE (Systemic Lupus Erythematosus) Suspect: Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
SLE (Systemic Lupus ... , macular, patchy ... Non-autoimmune rheumatologic ... and CNS • Headache ... #Diagnosis #Rheumatology
Approach to an Eye Exam 1. History 2. Obvious Physical Trauma 3. Initial Assessment A. Visual Acuity
Ocular Movements ... (CN 3, 4, 6) ... Slit Lamp Exam (SLE ... Anterior Chamber ... Blood Vessels #Ocular
Macrophage Activation Syndrome (MAS) Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH) What? A subset of
lupus erythematosus ... (CNS) dysfunction ... [SLE], AOSD) • ... #Diagnosis #Management ... #Hematology #Rheumatology
Behçet's Syndrome Systemic disease associated with inflammation of multiple organs, small-vessel vasculitis and large-vessel vasculopathy Epidemiology: • Young
Systemic disease ... Oral aphthae : SLE ... • Arthritis: SLE ... #diagnosis #management ... signs #symptoms #rheumatology
Blurry Vision - Differential Diagnosis Framework Anatomical Approach to Eye Disease: 1. Lids/Lashes 2. Extraocular Muscles/Motility 3. Conjunctiva/Sclera 4. Cornea 5. Anterior
Anterior Chamber ... Ocular Adverse Effects ... of Systemic Medications ... • Sjögren’s syndrome ... hyperviscosity syndrome
Vasculitis and Vasculitides - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions •
ischemia - Skin: erythematous ... • Cogan Syndrome ... lupus erythematosus ... vasculitis, and SLE ... differential #diagnosis #rheumatology
Sjogren's Syndrome Overview Epidemiology: • F > M: 9:1 • 5-6th Decades (can be any age) Autoimmune exocrinopathy multisystemic disease
overlaps with RA, SLE ... gland) biopsy • Ocular ... • 8%-27% for CNS ... #Rheumatology # ... Diagnosis #Management
Vasculitis - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions • Mononeuritis multiplex • Hematuria, proteinuria,
diseases, such as SLE ... ischemia • Skin: Erythematous ... chorioretinitis, CNS ... : Ocular inflammatory ... Differential #Diagnosis #Rheumatology
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