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diagnosis hematology rheumatology hemophagocytic lymphohistiocytosis syndrome achalasia activation algorithm antinxp2 antinxp2dm classification coagulation dermatomyositis dic disseminated enteropathy esophageal esophagus gangrenosum
Hemophagocytic Lymphohistiocytosis (HLH) Pathophysiology: Triggering factor (infection,...)→Activation of CD8 T cells (IFN-y) → Excessive activation of macrophages
accumulation of clinical ... Assessment • Clinical ... Treatment: • ... Lymphohistiocytosis #diagnosis #management ... #treatment #summary
Hemophagocytic Lymphohistiocytosis (HLH) Definition: Overwhelming clinical syndrome associated with excessive macrophage activation and cytokine storm due to
: Overwhelming clinical ... age, however the disease ... • Bicytopenia Treatment ... Lymphohistiocytosis #diagnosis #management ... #treatment #hematology
Hemophagocytic Lymphohistiocytosis (HLH) Treatment Primary HLH: - HLH-94 Protocol • Dexamethasone
) Treatment Primary ... or autoimmune disease ... for refractory disease ... #Treatment #management ... #hematology
Macrophage Activation Syndrome (MAS) Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH) What? A subset of
lymphohistiocytosis (HLH ... fever syndromes Clinical ... Fever is the main clinical ... Treatment: • Corticosteroids ... Syndrome #Diagnosis #Management
Algorithm regarding the diagnosis and treatment of Hereditary Hemochromatosis HH. Step 1: In the patient with
diagnosis and treatment ... of liver disease ... If other causes ... algorithm #diagnosis #management ... #hepatology #gastroenterology
Hodgkin's Lymphoma Overview Hodgkin's lymphoma (HL) is an uncommon hematological malignancy arising from mature B cells. It
Hodgkin Lymphoma - Clinical ... number of sites of disease ... Hodgkin Lymphoma Treatment ... classification #hematology ... #oncology #management
Disseminated Intravascular Coagulation (DIC) Overview Increased Clotting and Consumption of Clotting Factors Findings: • Bleeding • Recent history
organ damage Clinical ... • Severe Liver Disease ... Treat primary cause ... #treatment #management ... #hematology
Protein Losing Enteropathy Clinical Presentation: • Volume overload: Peripheral edema, pleural effusion or ascites. • Gl symptoms
Losing Enteropathy Clinical ... without apparent cause ... 1.5 - 3 g/kg) • Treatment ... Enteropathy #diagnosis #management ... #gastroenterology
SAPHO Syndrome Summary What? SAPHO syndrome is a rare chronic inflammatory disorder of bone, joint, and skin characterized
Rule out other causes ... and lower jaw Treatment ... osteoarticular and skin disease ... Rheumatology #diagnosis #management ... #Dermatology
Achalasia Summary Epidemiology: 10 cases per 100,000 individuals Defined by inadequate relaxation of the LES and aperistalsis Primary or
) Clinical Presentation ... Three clinical features ... Treatment options ... Achalasia #diagnosis #management ... #treatment #gastroenterology
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