10 results
Adrenoceptor Actions
α1
 • Vascular smooth muscle - Contraction
 • Genitourinary smooth muscle - Contraction
 • Intestinal
Adrenoceptor Actions ... • Heart - ↑ Chronotropy ... Lipolysis #Adrenoceptor
Calcium Channel Blockers - Dihydropyridines vs Non-Dihydropyridines
Dihydropyridines (amlodipine, felodipine, nifedipine, nicardipine)
 • SVR: Decrease
 • Inotropy:
: No effect • Chronotropy ... Inotropy: Decrease • Chronotropy
Clinician's Pocket Guide to Vasopressors - Receptor Profiles and Hemodynamic Parameters
 • Systemic Vascular Resistance -
contractions • Chornotropy
Pheochromocytoma - Diagnosis and Management Summary
10 percent rule = 10% of pheochromocytomas are extra-adrenal, multiple, bilateral,
-1 and alpha-2 adrenoceptors ... peripheral beta-2 adrenoceptors ... unopposed alpha-adrenoceptor
Recurrent Polymorphic VT/Torsades de Pointes - Management Algorithm
Drugs that prolong QT interval:
 • Class 1a (quinidine,
minutes Increasing chronotropy
Mean Arterial Pressure (MAP)

Average arterial pressure throughout one cardiac cycle, systole, and diastole. 
Surrogate indicator of
affected by the chronotropy ... afterload #Heartrate #chronotropy
Vasopressors and Inotropes - Pharmacology Summary
Vasopressors
Phenylephrine (alpha-1)
 • Increases BP, SVR
 • Risk of reflex bradycardia
not inotropic/chronotropic
Drugs with Actions on Bronchial Smooth Muscle
Bronchodilation is promoted by cAMP. Intracellular levels of cAMP can
increased by ß-adrenoceptor
Pacemaker Indications
Class I
 • Symptomatic sinus node dysfunction
 • 3° AV or type 2 2° AV
• Symptomatic chronotropic
Guideline-Directed Medical Therapy (GDMT) in HFrEF and CKD

 • Class I pillars of HFrEF GDMT across
sGC stimulator, Chronotropes