18 results
Rapidly Progressive Glomerulonephritis (RPGN)
RPGN has three primary pathophysiologic causes differentiated by immunofluorescence

Immune Complex Mediated (granular staining):
pathophysiologic causes ... staining): • Low Complement ... Post-strep GN, Lupus ... #Vasculitis #differential ... #diagnosis #algorithm
Causes of Hypocomplementemia - CHAMPS Mnemonic
C - Cryoglobulinemia (85%), C3 glomerulopathy, cirrhosis
H - Heavy Chain deposition
Causes of Hypocomplementemia ... , type 1 (50%-80% ... S - Systemic Lupus ... Hypocomplementemia #Low #Complement ... Mnemonic #diagnosis #differential
Lupus Nephritis Classification Algorithm

#Lupus #Nephritis #Classification #Algorithm #diagnosis #differential #types #rheumatology #nephrology #renal
Lupus Nephritis ... Classification Algorithm ... #Classification ... #differential # ... types #rheumatology
Hypersensitivity Types and Their Mechanisms
Type I - lgE - Soluble antigen
 - Allergen-specific lgE antibodies bind
antigen, leading to complement ... Complement activation ... Post-streptococcal glomerulonephritis ... , and systemic lupus ... #Classification
Summary table of types of hypersensitivity reactions. 
Type 1
 - Mediators: lgE
 - Antigen Form: Soluble
Allergen-specific lgE causes ... they activate complement ... Post-streptococcal glomerulonephritis ... , Systemic lupus ... allergy #table #classification
Causes of Hematuria - Differential Diagnosis Algorithm
Red blood cells on urine microscopy. Must exclude false positives
- Differential ... Diagnosis Algorithm ... IgA, post-strep, lupus ... • Lupus glomerulonephritis ... #Diagnosis #Algorithm
Causes of Diffuse Lymphadenopathy - Differential Diagnosis Algorithm
Reactive:
 - Systemic Inflammatory
     •
Causes of Diffuse ... Diagnosis Algorithm ... • Systemic Lupus ... #Diagnosis #Algorithm ... #Causes #Hematology
Causes of Acute Kidney Injury (AKI) - Differential Diagnosis Algorithm
Acute Kidney Injury (AKI) - Acute increase
Injury (AKI) - Differential ... Diagnosis Algorithm ... Rapidly Progressive Glomerulonephritis ... IgA, post-strep, lupus ... #Diagnosis #Algorithm
Lupus Nephritis Primer
Class I - Minimal Mesangial
Class II - Mesangial Proliferative
Class Ill - Focal Proliferative
Class IV
Lupus Nephritis ... Proliferative Class IV - Diffuse ... DrFlashHeart #Lupus ... Nephritis #SLE #Classification ... #Classes #differential
Cryoglobulinemia Summary

Cryoglobulins:
 • Cryoglobulins are Igs in the serum that precipitate in vitro at temperatures below
• They can cause ... Skin ulcers - Glomerulonephritis ... • Low serum C4 complement ... (e.g. systemic lupus ... #classification