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diagnosis differential dermatology rheumatology alopecia hairloss hematology nephrology types vasculitis allergy hypersensitivity lad localized lymphadenopathy management nephritis oncology reactions table
Lupus Nephritis Primer Class I - Minimal Mesangial Class II - Mesangial Proliferative Class Ill - Focal Proliferative Class IV
Lupus Nephritis ... Ill - Focal Proliferative ... Class IV - Diffuse ... Nephritis #SLE #Classification ... #Classes #differential
Rapidly Progressive Glomerulonephritis (RPGN) RPGN has three primary pathophysiologic causes differentiated by immunofluorescence Immune Complex Mediated (granular staining):
pathophysiologic causes ... staining): • Low Complement ... Post-strep GN, Lupus ... Idiopathic • Normal Complement ... differential #diagnosis #algorithm
Causes of Diffuse and Localized Lymphadenopathy - Differential Diagnosis Algorithm • Reactive (Inflammatory / Infectious) •
Causes of Diffuse ... Differential Diagnosis Algorithm ... Metastatic) #Diffuse ... #Focal #Localized ... #Causes #Hematology
Peripheral Neuropathy - Diagnostic Schema and Differential Diagnosis Hereditary Common Causes Rapid Onset Subacute/Chronic Onset - Multifocal - Focal -
Hereditary Common Causes ... Multifocal - Focal ... - Diffuse ... Diagnosis #Schema #Algorithm ... #Causes #neurology
Hair Loss (Alopecia) - General (Diffuse and Focal) Differential Diagnosis Algorithm DIFFUSE Scarring - Irreversible-biopsy required • Lupus
Diagnosis Algorithm ... Irreversible-biopsy required • Lupus ... • Discoid lupus ... Differential #Diagnosis #Algorithm ... #causes
Causes of Hypocomplementemia - CHAMPS Mnemonic C - Cryoglobulinemia (85%), C3 glomerulopathy, cirrhosis H - Heavy Chain deposition
Causes of Hypocomplementemia ... Membranoproliferative glomerulonephritis ... Post/pauci immune glomerulonephritis ... S - Systemic Lupus ... Hypocomplementemia #Low #Complement
Causes of Hematuria - Differential Diagnosis Algorithm Red blood cells on urine microscopy. Must exclude false positives
Causes of Hematuria ... Differential Diagnosis Algorithm ... IgA, post-strep, lupus ... • Lupus glomerulonephritis ... #Causes
Management of Lupus Nephritis Lupus nephritis (LN) in 10 to 40% of SLE Hallmark = proteinuria 20.5 g/g
severity (ISN/RPS classification ... by 12 months Classification ... Ill - Focal LN ... IV - Diffuse LN ... glomeruli) Diffuse
Summary table of types of hypersensitivity reactions. Type 1 - Mediators: lgE - Antigen Form: Soluble
Allergen-specific lgE causes ... chain causing local ... Post-streptococcal glomerulonephritis ... , Systemic lupus ... allergy #table #classification
Causes of Diffuse Lymphadenopathy - Differential Diagnosis Algorithm Reactive: - Systemic Inflammatory •
Causes of Diffuse ... Differential Diagnosis Algorithm ... • Systemic Lupus ... Hodgkin's Lymphoma #Diffuse ... #Causes #Hematology
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