35 results
Rapidly Progressive Glomerulonephritis (RPGN)
RPGN has three primary pathophysiologic causes differentiated by immunofluorescence

Immune Complex Mediated (granular staining):
pathophysiologic causes ... staining): • Low Complement ... Post-strep GN, Lupus ... Idiopathic • Normal Complement
Drug Induced Lupus vs SLE
Drug Induced Lupus (DIL):
 • Epidemiology: -10% of all lupus cases, drug-dependent,
Drug Induced Lupus ... cases, drug-dependent ... 90% - Low complement ... Discontinuation of causal ... 80% - Low complement
Causes of Hypocomplementemia - CHAMPS Mnemonic
C - Cryoglobulinemia (85%), C3 glomerulopathy, cirrhosis
H - Heavy Chain deposition
Causes of Hypocomplementemia ... S - Systemic Lupus ... Hypocomplementemia #Low #Complement
Systemic Lupus Erythematosus (SLE) - Diagnosis and Management Summary
 • Epidemiology: 10-180/100,000, Typically Age 20-40, F:M
Systemic Lupus Erythematosus ... , oral ulcers, Lupus ... Positive in 60-80% of cases ... 80% - Low complement ... Lupusreference #SLE #lupus
Constrictive Pericarditis on POCUS Echocardiogram - Apical 3-Chamber View

Young Lupus patient admitted to hospital new onset
Pericarditis on POCUS ... View Young Lupus ... could pinpoint the cause ... Lupus pericarditis ... clinical #cardiology #A3C
Papillary muscle rupture on POCUS Echocardiogram - A4C

Rare case! 70M recent MI with acute resp failure
muscle rupture on POCUS ... Echocardiogram - A4C ... Rare case! ... muscle rupture on POCUS ... Echocardiogram #A4C
Constrictive Pericarditis on POCUS Echocardiogram - Subcostal View

Young Lupus patient admitted to hospital new onset HFpEF.
Pericarditis on POCUS ... View Young Lupus ... could pinpoint the cause ... Lupus pericarditis ... clinical #cardiology #s4C
Myocarditis on Echocardiogram
It is always great to witness the tremendous reversal of severe biventricular dysfunction from
Case Resolution: ... Myocarditis #plax #psax #a4c ... clinical #cardiology #pocus
Takotsubo Cardiomyopathy - Right Ventricular Involvement 

In up to 1/4 of cases of stress cardiomyopathy (takotsubo),
In up to 1/4 of cases ... Echocardiogram #A4C ... #Clinical #POCUS
Summary table of types of hypersensitivity reactions. 
Type 1
 - Mediators: lgE
 - Antigen Form: Soluble
Allergen-specific lgE causes ... antigens, leading to complement ... they activate complement ... glomerulonephritis, Systemic lupus