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clinical diagnosis ultrasound pulmonary differential echocardiogram cardiology rheumatology effusion management a4c complex pericardial sle cardiac classification jugular pericarditis plax vasculitis
Rapidly Progressive Glomerulonephritis (RPGN) RPGN has three primary pathophysiologic causes differentiated by immunofluorescence Immune Complex Mediated (granular staining):
pathophysiologic causes ... staining): • Low Complement ... Post-strep GN, Lupus ... Idiopathic • Normal Complement
Drug Induced Lupus vs SLE Drug Induced Lupus (DIL): • Epidemiology: -10% of all lupus cases, drug-dependent,
Drug Induced Lupus ... cases, drug-dependent ... 90% - Low complement ... Discontinuation of causal ... 80% - Low complement
Causes of Hypocomplementemia - CHAMPS Mnemonic C - Cryoglobulinemia (85%), C3 glomerulopathy, cirrhosis H - Heavy Chain deposition
Causes of Hypocomplementemia ... S - Systemic Lupus ... Hypocomplementemia #Low #Complement
Interstitial Lung Diseases (ILD) Exposure-Related ILD (a.k.a. extrinsic allergic alveolitis): • Hypersensitivity pneumonitis, Farmer's lung, Bird
Interstitial Lung ... Bird fanciers' lung ... ILD caused by inhalation ... Polymyositis-dermatomyositis, Lupus ... differential #pulmonary #causes
Systemic Lupus Erythematosus (SLE) - Diagnosis and Management Summary • Epidemiology: 10-180/100,000, Typically Age 20-40, F:M
Systemic Lupus Erythematosus ... , oral ulcers, Lupus ... Positive in 60-80% of cases ... 80% - Low complement ... Lupusreference #SLE #lupus
Causes of Interstitial Lung Disease - Differential Diagnosis Algorithm Idiopathic Interstitial Pneumonia • (UIP) Usual Interstitial Pneumonia
Causes of Interstitial ... Lung Disease - ... Metastases to lung ... Arthritis, Systemic Lupus ... Diseases #ILD #Causes
Bilateral B-Lines in case of Pneumonia on Lung POCUS Young healthy pt with fever/dyspnea. POCUS lung exam
Bilateral B-Lines in case ... POCUS Young ... POCUS lung exam ... Lung POCUS shows ... Lung POCUS invaluable
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 SLE (Systemic Lupus Erythematosus) Suspect: Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
anti-Smith Ab, low complements ... Clinical Features: Lungs ... hemorrhage • Shrinking lung ... RNP antibodies, Complement ... and leukemia • Lung
Hemoptysis - Differential Diagnosis Framework Airways: • Bronchitis • Bronchiectasis • Malignancy: Primary bronchogenic CA, Endobronchial
westermani, PNA, Lung ... Goodpastures, Lupus ... Diagnosis #pulmonary #causes
Great Mimickers - SHALLOTS Mnemonic S- Syphilis - Neurosyphilis, aortitis, gummas... Granulomas can form anywhere! Skin, mucosa,
joints, bones, lungs ... What doesn't HIV cause ... anything L - Lupus ... Could be lupus in ... consumption- number one cause
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