39 results
SLICC SLE Diagnostic Criteria - Systemic Lupus Erythematosus
Clinical and Immunologic Criteria

CLINICAL CRITERIA
 - ACUTE CUTANEOUS LUPUS
Criteria - Systemic Lupus ... ACUTE CUTANEOUS LUPUS ... determined by Positive test ... - Low complement ... Direct Coombs’ test
Rapidly Progressive Glomerulonephritis (RPGN)
RPGN has three primary pathophysiologic causes differentiated by immunofluorescence

Immune Complex Mediated (granular staining):
pathophysiologic causes ... staining): • Low Complement ... Post-strep GN, Lupus ... Idiopathic • Normal Complement
Drug Induced Lupus vs SLE
Drug Induced Lupus (DIL):
 • Epidemiology: -10% of all lupus cases, drug-dependent,
Drug Induced Lupus ... cases, drug-dependent ... 90% - Low complement ... Discontinuation of causal ... 80% - Low complement
HINTS Exam - Abnormal Head Impulse Test = Peripheral Cause

This video demonstrates:
1) Normal Head Impulse Test
= Peripheral Cause ... This video demonstrates ... for a PERIPHERAL cause ... Video by Dr. ... PhysicalExam #Clinical #Video
Causes of Hypocomplementemia - CHAMPS Mnemonic
C - Cryoglobulinemia (85%), C3 glomerulopathy, cirrhosis
H - Heavy Chain deposition
Causes of Hypocomplementemia ... S - Systemic Lupus ... Hypocomplementemia #Low #Complement
Systemic Lupus Erythematosus (SLE) - Diagnosis and Management Summary
 • Epidemiology: 10-180/100,000, Typically Age 20-40, F:M
Systemic Lupus Erythematosus ... , oral ulcers, Lupus ... Positive in 60-80% of cases ... 80% - Low complement ... Lupusreference #SLE #lupus
HINTS Exam - Abnormal Test of Skew (Abnormal Vertical Skew)

In a patient with vertigo symptoms, this
Exam - Abnormal Test ... for a CENTRAL cause ... Video by Dr. ... Vertical #Skew #Test ... PhysicalExam #Clinical #Video
HINTS Exam - Abnormal Head Impulse Test = Peripheral Cause

This video demonstrates:
1) Normal Head Impulse Test
= Peripheral Cause ... This video demonstrates ... for a PERIPHERAL cause ... Video by Dr. ... PhysicalExam #Clinical #Video
Summary table of types of hypersensitivity reactions. 
Type 1
 - Mediators: lgE
 - Antigen Form: Soluble
Allergen-specific lgE causes ... antigens, leading to complement ... they activate complement ... glomerulonephritis, Systemic lupus ... dermatitis, Tuberculin test
HINTS Exam - Normal Test of Skew (Normal Vertical Skew)

In a patient with vertigo symptoms, this
Exam - Normal Test ... for a PERIPHERAL cause ... Video by Dr. ... Vertical #Skew #Test ... PhysicalExam #Clinical #Video