1428 results
Membranoproliferative Glomerulonephritis (MPGN) AKA: Mesangiocapillary GN
 • Active Urine Sediment (dysmorphic RBC, RBC casts, +/- proteinuria)
staining (lg + complement ... MGPN • Complement ... of alternative complement ... MPGN without complement ... Glomerulonephritis #MPGN #nephrology
Pathogenesis of PLA2R-associated (primary) Membranous Nephropathy

Immune deposits  → Activate complement  → C5b-9 complex
deposits → Activate complement ... pathophysiology #nephrology
Comprehensive pathogenesis of IgA Nephropathy (i.e Berger’s Disease). 

IgA Nephropathy is the most common cause of
Relationship of complement ... IgANephropathy #Nephrology
Recommended initial testing for patients being evaluated for glomerular disease 

24-hour urine collection - Quantify proteinuria.
or alternative complement ... nephrotic #nephritic #nephrology
Recommended initial testing for patients being evaluated for glomerular disease
1) 24-hour urine collection - Quantify proteinuria.
or alternative complement ... initial #testing #nephrology
Complement Pathways
- Classical Pathway
- Lectin Pathway
- Alternative Pathway

#Complement #Pathway #hematology #pathophysiology
Complement Pathways ... Alternative Pathway #Complement
Overview of the Complement System - Classical and Alternative Pathways

by Dr.Grace Leo @gracie_leo

#Complement #System #Classical #Alternative
Overview of the Complement ... gracie_leo #Complement
Infectious Risks in Asplenia and Deficiencies in Humoral Immunity and Complement - Venn Diagram
Humoral Immunity:
 •
Humoral Immunity and Complement ... T and B cells Complement ... PrathitKulkarni #complement
C5-C9 Deficiency - Pathogenesis and Clinical Findings
Note:
 • Risk of invasive meningococcal disease is 1000-10000x higher
is rare Normal complement ... response: The complement ... activation -> Complement ... C7, C8, C9 -> Complement ... C5C9Deficiency #Complement
Inflammatory Cascade: Pathogenesis and Clinical Findings
Continued Innate Immunity
 • Phagocytosis: (main mechanism) neutrophils and macrophages engulf
dead tissue • Complement ... activation of complement