19 results
Hypersensitivity Types and Their Mechanisms
Type I - lgE - Soluble antigen
 - Allergen-specific lgE antibodies bind
- Local and systemic ... , seasonal hay fever ... #Classification ... #Pathophysiology ... Diagnosis #Reactions #Table
Summary table of types of hypersensitivity reactions. 
Type 1
 - Mediators: lgE
 - Antigen Form: Soluble
Summary table of ... Anaphylaxis, Hay fever ... glomerulonephritis, Systemic ... #allergy #table ... #classification
Hypersensitivity: Summary
Type I Hypersensitivity:
 • Immunological Mediator: lgE
 • Immunological Target: Allergen Molecules
 • Ex: Antibiotic
Hypersensitivity: Summary Type ... peanuts), Hay fever ... conjunctivitis Type ... complexes • Ex: Systemic ... #Classification
Cryoglobulinemia Summary

Cryoglobulins:
 • Cryoglobulins are Igs in the serum that precipitate in vitro at temperatures below
activate the immune system ... Types: • Type ... • Low serum C4 complement ... disorder (e.g. systemic ... #classification
EULAR/ACR Classification Criteria for Systemic Lupus Erythematosus
Clinical Domains:
 • Constitutional domain: Fever
 • Cutaneous domain: Non-scarring
EULAR/ACR Classification ... Criteria for Systemic ... Constitutional domain: Fever ... anticoagulant • Complement ... Criteria #SLE #Systemic
C5-C9 Deficiency - Pathogenesis and Clinical Findings
Note:
 • Risk of invasive meningococcal disease is 1000-10000x higher
is rare Normal complement ... response: The complement ... susceptibility to systemic ... tissue -> Fatigue, fever ... #pathophysiology
Type I Hypersensitivity: Pathogenesis and clinical findings
Definition: Production of lgE Antibodies that bind to harmless allergens
Type I Hypersensitivity ... Patient's immune system ... peanuts) • Hay fever ... Anaphylaxis #TypeI ... Allergy #Immunology #pathophysiology
Lymphomas and Lymphoproliferative Disorders - Differential Diagnosis Algorithm
Hodgkin Lymphoma ~40% - Characteristic For Reed-Sternberg (RS) Cells
Differential Diagnosis Algorithm ... site in lymphatic system ... with lymphatic system ... Lymphoproliferative #Disorders #Classification ... #pathophysiology
Suspected catheter-related bloodstream infection - Management Algorithm
 • Temperature 37.8 C   • Rigors
infection - Management Algorithm ... weeks of tailored systemic ... • Persistent fever ... • Persistent fever ... infection #Management #Algorithm
Vasculitis and Vasculitides - Differential Diagnosis Framework

When to Consider Vasculitis:
 • Purpura, ischemic skin lesions
 •
Coronary arteries - Fever ... central nervous system ... Vasculitis: • Fevers ... against MPO • Complement ... #rheumatology #classification