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diagnosis differential cardiac classification clinical complications echocardiogram effusion pericardial signs sle symptoms tamponade a4c algorithm cryoglobulinemia cryoglobulins erythematosus glomerulonephritis management
Rapidly Progressive Glomerulonephritis (RPGN) RPGN has three primary pathophysiologic causes differentiated by immunofluorescence Immune Complex Mediated (granular staining):
three primary pathophysiologic ... causes differentiated ... immunofluorescence Immune Complex ... Post-strep GN, Lupus ... Glomerulonephritis #Vasculitis
Systemic Lupus Erythematosus (SLE): Musculoskeletal Manifestations • Immune Complex Deposition - Arthralgia, Arthritis
Systemic Lupus Erythematosus ... Manifestations • Immune Complex ... Myopathy (Also caused ... Erythematosus #SLE #MSK ... Complications #pathophysiology
Vasculitis and Vasculitides - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions •
tracts Immune Complex ... tract, and often causes ... inflammation Others: • Lupus ... such as systemic lupus ... differential #diagnosis #rheumatology
Lupus (SLE): Mucocutaneous Manifestations • Langerhan cells and keratinocytes release cytokines -> localized inflammatory response ->
Lupus (SLE): Mucocutaneous ... hair follicles -> causes ... inflammation (complex ... Livedo Reticularis, Vasculitis ... Manifestations #pathophysiology
Cryoglobulinemia Summary Cryoglobulins: • Cryoglobulins are Igs in the serum that precipitate in vitro at temperatures below
deposit of immune complexes ... • They can cause ... Cryoglobulins Cause ... (e.g. systemic lupus ... classification #rheumatology
Transverse Myelitis Overview Focal inflammatory disorder of the spinal cord resulting in rapid onset of weakness, sensory
10-33% develop MS ... monophasic Pathophysiology ... • Infectious causes ... virus - Herpes simplex ... - Sjogren - Vasculitis
Complex Pericardial Effusion with Tamponade on POCUS Echocardiogram - PLAX Pt sent to ED c intradialytic hypotension.
Complex Pericardial ... with Tamponade on POCUS ... ESRD d/t Lupus nephritis ... RJonesSonoEM #Complex ... PLAX #clinical #cardiology
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 Complex Pericardial Effusion with Tamponade on POCUS Echocardiogram - A4C Pt sent to ED c intradialytic hypotension.
Complex Pericardial ... with Tamponade on POCUS ... ESRD d/t Lupus nephritis ... RJonesSonoEM #Complex ... A4C #clinical #cardiology
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