21 results
Hypersensitivity: Definitions
 • Type I - Production of lgE Abs that bind to harmless allergens and
cell surfaces causes ... antigen-surface complex ... antibody-antigen complexes ... causes development ... #Types #Classification
Type III Hypersensitivity: Pathogenesis and clinical findings
Definition: Small antigen-antibody complexes (produced from normal immune response to
antigen-antibody complexes ... self-antigens are the cause ... antigens are the cause ... HypersensitivityReaction #Allergy ... #Immunology #pathophysiology
Summary table of types of hypersensitivity reactions. 
Type 1
 - Mediators: lgE
 - Antigen Form: Soluble
lgE causes mast-cell ... Antigen-antibody complex ... Antigen-antibody complexes ... reactions #types #allergy ... #table #classification
Hypersensitivity Types and Their Mechanisms
Type I - lgE - Soluble antigen
 - Allergen-specific lgE antibodies bind
When the specific allergen ... Antigen-antibody complexes ... Hypersensitivity #Types #Classification ... #Pathophysiology ... #Allergy #Diagnosis
Systemic Lupus Erythematosus (SLE): Musculoskeletal Manifestations

 • Immune Complex Deposition
    - Arthralgia, Arthritis
Manifestations • Immune Complex ... Myopathy (Also caused ... Complications #pathophysiology ... #signs #symptoms
Pott's Disease in Tuberculosis - Diagnosis and Management Summary
Epidemiology:
 - Typically from TB endemic areas
 -
extrapulmonary cases ... Clinical Signs ... years - May have signs ... decreased reflexes Pathophysiology ... Mycobacterium tuberculosis complex
Hypochloremia - Differential Diagnosis Algorithm

Cause - Decreased Intake:
 • Low salt in diet
 • Exclusive D5W
Differential Diagnosis Algorithm ... - Gitelman SIGNS ... homeostasis is complex ... Differential #Diagnosis #Algorithm ... #Pathophysiology
Rapidly Progressive Glomerulonephritis (RPGN)
RPGN has three primary pathophysiologic causes differentiated by immunofluorescence

Immune Complex Mediated (granular staining):
three primary pathophysiologic ... causes differentiated ... immunofluorescence Immune Complex ... differential #diagnosis #algorithm
Polyarteritis Nodosa (PAN): Pathogenesis and Clinical Findings

Medical Comorbidities Malignancies (most commonly hairy-cell leukemia)
Immunogenetic Predisposition: patient is
antigen-antibody complexes ... Viral replication causes ... PolyarteritisNodosa #Pathophysiology ... #Diagnosis #Signs
IgA Vasculitis – Henoch Scholein Purpura: Pathogenesis and Clinical Findings

 - Infectious Agents - 50% have
adhesion of IgA complexes ... Formation of immune complexes ... periumbilical region), nausea ... HenochScholeinPurpura #Pathophysiology ... #Diagnosis #Signs