21 results
ACEI Antihypertensive Dose Comparison. Consider divided (BID) regimen for better pre-dose (trough) BP control for the
ACEI Antihypertensive ... Dose Comparison ... the following ACEIs ... Monitor BP, potassium ... #PrimaryCare #Comparison
HFrEF: Guideline Directed Medical Therapy

"Must Be On"
 • ACEI, ARB, or ARNI AND select Beta Blockers
Must Be On" • ACEI ... before increasing ACEI ... Reducing: • ACEI ... hfref #management #medications
Heart Failure (HFrEF) Treatment - GDMT for stage C 

For patients with Heart Failure with REDUCED
getting patients on medication ... initiate them on ACEI ... both of these medications ... maximally tolerated ACEI ... Entresto (replacing ACEI
ACEI or ARB Initiation
Hyperkalemia:
 - Review concurrent drugs
 - Moderate potassium Intake
 - Consider: diuretics, sodium
ACEI or ARB Initiation ... drugs - Moderate potassium ... Reassess concomitant medications ... artery stenosis #ACEI
Here’s a review of the Renin-Angiotensin-Aldosterone system (RAAS)

This is a very common pathway that clinicians should
with excreting potassium ... classes (Aliskiren, ACEI ... while retaining potassium ... will increase potassium ... , which is why potassium
Mechanisms of Drug-Induced Hyperkalemia 
 • Direct renin inhibitor (Aliskiren)
 • Renin release inhibition (NSAIDs, Beta-Blockers)
Angiotensin-converting enzyme (ACE ... #pharmacology #potassium ... #medications #druginduced
Antiseizure Drugs 
Sodium Channel Blockers: Carbamazepine, Oxcarbazepine, Eslicarbazepine, Lamotrigine, Lacosamide, Phenytoin, fosphenytoin
Broad Spectrum: Valproate, Levetiracetam, Brivaracetam,
Tiagabine, Vigabatrin Potassium ... antiepileptic #medications ... #pharmacology #comparison
Drug Induced Kidney Injury
 • Pre-Renal: NSAIDS, CNI, ACEI/ARB, IL-2 therapy, Diuretics CAR-T therapy
 • Osmotic
: NSAIDS, CNI, ACEI ... algorithm #nephrology #Medications
A toxidrome is a syndrome (set of symptoms) caused by specific medications or toxins.

There are 5
caused by specific medications ... (pilocarpine), AChEIs ... Toxicology #Toxidromes #Comparison
Compelling and Possible Contraindications to Antihypertensive Drugs
Diuretics (thiazides)
 - Gout
 - Metabolic syndrome, Glucose intolerance, Pregnancy,
hyperkalemia (ACEI ... ARB, diabetes) ACE ... failure - Co-medication ... antihypertensive #medications