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diagnosis management rheumatology dermatology lupus erythematosus photo syndrome systemic activation adultonset antinxp2 antinxp2dm behcet classification comparison cutaneous dermatomyositis druginduced hand
Adult-Onset Still's Disease Clinical triad: Fever, Arthralgia/arthritis, Skin rash ± odynophagia + Biological inflammation: Increased neutrophils, Hyperferritinemia, decreased
Clinical triad ... arthritis, Skin rash ... fraction < 20% Differential ... diagnosis #management #treatment ... #rheumatology
Systemic Lupus Erythematosus (SLE) - Diagnosis and Management Summary • Epidemiology: 10-180/100,000, Typically Age 20-40, F:M
40, F:M 9:1 • Clinical ... Manifestations: Malar rash ... life-threatening • Treatment ... Evolution: Chronic disease ... Management #Summary #rheumatology
SLE (Systemic Lupus Erythematosus) Suspect: Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
) Suspect: Clinical ... permanent alopecia Differential ... Malignancy (e.g. hematologic ... lymphoproliferative syndrome Clinical ... vein thrombosis Hematologic
Drug Induced Lupus vs SLE Drug Induced Lupus (DIL): • Epidemiology: -10% of all lupus cases, drug-dependent,
to 1:1 F:M • Clinical ... NPSLE rare, Malar rash ... 40, F:M 9:1 • Clinical ... Manifestations: Malar rash ... Evolution: Chronic disease
Macrophage Activation Syndrome (MAS) Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH) What? A subset of
fever syndromes Clinical ... Fever is the main clinical ... Petechial or purpuric rash ... erythematosus [SLE ... Treatment: • Corticosteroids
Behçet's Syndrome Systemic disease associated with inflammation of multiple organs, small-vessel vasculitis and large-vessel vasculopathy Epidemiology: • Young
association • M > F Clinical ... ) Differential Diagnosis ... Oral aphthae : SLE ... • Arthritis: SLE ... Arthritis, AS Treatment
Cutaneous larva migrans skin Rash 25 F recent Caribbean vacation, walked barefoot on sand and now with
Diagnosis is clinical ... No treatment is ... rates of recurrent disease ... larva #migrans #skinRash ... #dermatology #clinical
Vancomycin induced Leukocytoclastic Vasculitis (LCV) of the Hand 70 M vertebral osteomyelitis on vancomycin and cefepime for
diffuse palpable rash ... Differential for ... myxoma, Behcet disease ... Vasculitis #LCV #Hand #skinrash ... #dermatology #clinical
Hodgkin's Lymphoma Overview Hodgkin's lymphoma (HL) is an uncommon hematological malignancy arising from mature B cells. It
Hodgkin Lymphoma - Clinical ... supraclavicular node • Anterior ... number of sites of disease ... Hodgkin Lymphoma Treatment ... classification #hematology
Anti-NXP-2 Dermatomyositis What? DM with generalized subcutaneous edema Pts have more myalgias, more severe weakness, and an increased prevalence
(blue-purple) rash ... the face, or the anterior ... auricular papules Clinical ... had more severe disease ... positive patients Treatment
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