34 results
Causes of Bone/Joint Pain in Sickle Cell Disease
Vaso-occlusive pain:
 • Mechanism: ischemic pain
 • Can present
Avascular necrosis ... • Differentiate ... SickleCell #Disease #differential ... #diagnosis #causes ... #hematology
Diagnosis and management of Polyarteritis Nodosa (PAN)

Chapel Hill 2012 definition: 
Necrotizing vasculitis ofmedium or small arteries
Diagnosis and management ... TerrierBen #PAN ... PolyarteritisNodosa #Rheumatology ... #Diagnosis #Management ... #Vasculitis #Differential
Vasospastic (Prinzmetal) Angina
Definition / Epidemiology:
 • Rest angina attributed to coronary artery vasospasm.
 • Patients often
Pathophysiology: ... • Vascular smooth ... anginal chest pain ... tolerance • Pain ... #management
Aortic Dissection Pearls
Aortic dissection is caused by a tear in the tunica intima, the innermost layer
chest/abd/back pain ... Marfans, EDS ... Pulse deficit/differential ... Aortic #Dissection #diagnosis ... #management #vascular
Primary and Secondary Headaches - Red Flags and Differential Diagnosis
Red Flags (SNOOP):
S - Systemic		
N - Neurologic
Red Flags and Differential ... Diagnosis Red ... Eye/Temple • Pain ... quickly, deep pain ... primary #secondary #management
Approach to Joint Pain - Arthritis Differential Diagnosis Framework

Inflammatory Versus Noninflammatory Pain
 • Is it inflammatory
- Arthritis Differential ... Diagnosis Framework ... #Differential # ... Diagnosis #MSK # ... rheumatology #Monoarticular
Differentiation Syndrome in APML
Epidemiology:
 • Incidence: common in APL (2-48% depending on the study)
 • Triggers:
ATRA treatment Pathophysiology ... Cathepsin G release → vascular ... effusions, weight gain ... initiation • Differential ... #management #hematology
Adult-Onset Still's Disease
Clinical triad: Fever, Arthralgia/arthritis, Skin rash ± odynophagia
+ Biological inflammation: Increased neutrophils, Hyperferritinemia, decreased
fraction < 20% Differential ... Diaqnoses: • ... abnormalities • Muscular ... #management #treatment ... #rheumatology
Bradycardia
1) First Steps: IV, O2, Monitors, ECG, Pads on patient, Crash Cart in room. Is patient
from CHF, Chest Pain ... Administer sedative & pain ... #bradycardia #diagnosis ... #differential # ... management #cardiology
Acute Fatty Liver of Pregnancy (AFLP)
Pathophysiology:
 • Defect in fetal free fatty acid metabolism products →
Pregnancy (AFLP) Pathophysiology ... vomiting, abdominal pain ... infiltration) Differential ... Diagnosis: Viral ... #management #pathophysiology