8 results
Thrombocytopenia and Pregnancy - TTP/HUS, HELLP Syndrome and Acute Fatty Liver of Pregnancy (AFLP)
Three syndromes in
- TTP/HUS, HELLP ... (AFLP) Three syndromes ... #AFLP #obstetrics ... #hematology #diagnosis ... #table #comparison
Liver Disease in Pregnancy
Intrahepatic Cholestasis of Pregnancy (ICP)
 • Onset/Trimester: 25-32 weeks
 • Typical clinical features:
, no necrosis HELLP ... (AFLP) • Onset ... #hepatitis #comparison ... #differential #diagnosis ... #icp #HELLP #AFLP
Thrombocytopenia and Pregnancy
Three syndromes in the critically ill pregnant woman who presents with coagulation defects.
1) HELLP
#TTPHUS #HELLP ... #AFLP #Obstetrics ... #OBGyn #Hematology ... #Diagnosis #Comparison ... #Table
Elevated Liver Enzymes - Differential Diagnosis Algorithm
Severe ALT > 15x ULN
 • Viral
 • Drugs/Toxins
 •
- Differential Diagnosis ... • Wilson's • Pregnancy ... - AFLP, HELLP ... • Alcoholic hepatitis ... Others #LFTs #Hepatology
Causes of Acute Liver Injury - Differential Diagnosis
Hepatocellular - Liver Parenchyma
 • Infectious: Hepatitis C, A,
- Differential Diagnosis ... biliary obstruction, HELLP ... Vasculature • Hepatic ... Congestion/CHF • Hepatic ... Toxic: Medication, Pregnancy
Acute Fatty Liver of Pregnancy (AFLP)
Pathophysiology:
 • Defect in fetal free fatty acid metabolism products →
Fatty Liver of Pregnancy ... (AFLP) Pathophysiology ... : Viral Hepatitis ... Preeclampsia, HELLP ... #obgyn #diagnosis
Acute Liver Injury - Differential Diagnosis Algorithm

Vascular Causes of Acute Liver Injury: 
 • Hepatic vein:
- Differential Diagnosis ... Liver Injury: • Hepatic ... Venoocclusive disease • Hepatic ... melanoma, myeloma • Pregnancy ... : HELLP • Iatrogenic
Primary Biliary Cirrhosis (PBC) - Summary

PBC Epidemiology:
 • Female:Male 9:1
 • Common European descent
 • Age:
obstruction • ALP ... : • Viral hepatitis ... cholestasis of pregnancy ... malignancies, Hepatic ... #workup #hepatology