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hematology algorithm classification platelets dementia geriatrics high hyperkalemia mds mncd myelodysplasia myelodysplastic oncology potassium secondary subtypes syndromes
Causes of Thrombocytosis - Differential Diagnosis Secondary Thrombocytosis (a.k.a Reactive Thrombocytosis): • Acute infection • Solid organ
Causes of Thrombocytosis ... - Differential ... malignancies • Anemia ... specifically: iron deficiency ... Diagnosis #Causes
Thrombocytosis - Differential Diagnosis Platelet Count > 450 Reactive: • Anemia/blood loss (Fe deficiency) • Infection/Sepsis • Non-infectious
Thrombocytosis - ... Differential Diagnosis ... Reactive: • Anemia ... blood loss (Fe deficiency ... Diagnosis #causes
Causes of Thrombocytosis - Differential Diagnosis Algorithm Spurious: • Artifact (redo CBC) Autonomous: • Essential thrombocytosis • Polycythemia
Causes of Thrombocytosis ... - Differential ... Diagnosis Algorithm ... malignancy • Iron deficiency ... anemia #Thrombocytosis
Approach to Thrombocytosis - Elevated Platelet Count - Differential Diagnosis Algorithm Peripheral Smear concerning for malignancy?
Platelet Count - Differential ... Diagnosis Algorithm ... hematology for workup ... Acute hemolysis, deficiency ... anemia, Rebound
Major neurocognitive disorders (MNCD): Diagnosis and workup 1) Clinical diagnosis Cognitive impairment + loss of autonomy 2)
Whipple, vitamin deficiency ... Alzheimer - 1st cause ... - Progressive amnesia ... Dementia - 2nd cause ... MNCD #Dementia #Differential
Myelodysplastic Syndromes (MDS) What? Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
formed or don’t work ... or folic acid deficiency ... Workup: • Complete ... blood count with differential ... Myelodysplastic #Syndromes #diagnosis
Causes of Hyperkalemia l. Pseudohyperkalemia A Cellular efflux; thrombocytosis, erythrocytosis, leukocytosis, in vitro hemolysis B.
Causes of Hyperkalemia ... Cellular efflux; thrombocytosis ... aldosterone synthase deficiency ... #Hyperkalemia #Differential ... #Diagnosis #High
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