8 results
Growth Hormone Excess - Pathogenesis and clinical findings
 • Acromegaly and gigantism share the same pathophysiology
clinical findings • Acromegaly ... share the same pathophysiology ... diagnosis #signs #symptoms ... #endocrinology ... #pathophysiology
Acromegaly 
Caused by over-secretion of growth hormone (GH) from the pituitary gland. 
The condition is rare
Acromegaly Caused ... (GH) from the pituitary ... #Acromegaly #Signs ... #Symptoms #Diagnosis ... #Endocrinology
Clinical Effects of Large and Small Pituitary Tumours
Local complications - Headache, Visual field defect, Disconnection hyperprolactinaemia,
Large and Small Pituitary ... apoplexy) Hormone excess ... Hypogonadism • Acromegaly ... Tumors #Signs #Symptoms ... #Diagnosis #Endocrinology
Feedback Loop: Growth Hormone (GH)
Growth Hormone:
 • Liver -> GHR activates JAK-STAT pathway -> Incr IGF1
lipolysis Signs/Symptoms ... lipid • GH excess ... - Giantism or acromegaly ... #pathophysiology ... #pituitary
Acromegaly - Diagnosis and Management Summary - GrepMed Handbook 

Clinical Presentation: 
 • Classic Acromegaly: frontal
- If GH excess ... malignancy Pathophysiology ... islet cell tumor, excess ... Diagnosis #Management #Endocrinology ... #Treatment #Pathophysiology
Primary Hyperthyroidism - Pathogenesis and Clinical Findings

Note: Although rare, gestational diseases can lead to thyrotoxicosis due
thyrotoxicosis due to excess ... production by the pituitary ... Signs/Symptoms: ... Hyperthyroidism #endocrinology ... #pathophysiology
Diabetes Insipidus vs Syndrome of Inappropriate ADH (SIADH) - Comparison Table

Diabetes Insipidus - Inadequate ADH
SIADH -
Inadequate ADH SIADH - Excess ... Comparison #Table #Pathophysiology ... #Signs #Symptoms ... #Diagnosis #Endocrinology
Pituitary Mass Effects - Pathogenesis and Clinical Findings
 • Pituitary turnors are almost always a benign
Pituitary Mass Effects ... Pituitary adenomas ... Signs / Symptoms ... #SideEffects #endocrinology ... mnemonic #GLFTAP #pathophysiology