13 results
Low Alkaline Phosphatase - Hypophosphatasia 

Is Low Alkaline Phosphatase Of Clinical Importance?

ALP enzyme- Discovered in 1923
Low
Low Alkaline Phosphatase ... collection with EDTA Pathophysiology ... mineralization Symptoms ... of Low Alkaline ... respiratory failure • Neurologic
Gestational Hypertension & Preeclampsia

Gestational Hypertension (gHTN) 
• BP > 140/90 
• Onset > 20 wks gestation
• Elevated AST/ALT ... • Pulmonary edema ... Cerebral/visual symptoms ... • Elevated AST/ALT ... #Preeclampsia #Classification
Primary Biliary Cirrhosis (PBC) - Summary

PBC Epidemiology:
 • Female:Male 9:1
 • Common European descent
 • Age:
65 years PBC Pathophysiology ... PBC Signs and Symptoms ... PBC Labs: • Alkaline ... Nucleotidase • ALT ... obstruction • ALP
Pott's Disease in Tuberculosis - Diagnosis and Management Summary
Epidemiology:
 - Typically from TB endemic areas
 -
Clinical Signs/Symptoms ... of active pulmonary ... decreased reflexes Pathophysiology ... should be done in ALL ... for concomitant pulmonary
Dermatomyositis (DM) and Polymyositis (PM): Pathogenesis and clinical findings
Elevated Antinuclear Antibodies: Anti-Jo-1, Anti-OJ, Anti-Mi2, Anti-SRP, Anti-EJ,
aminotransferase (AST), and alanine ... aminotransferase (ALT ... PM #Diagnosis #Pathophysiology ... #Signs #Symptoms
Lymphomas and Lymphoproliferative Disorders - Differential Diagnosis Algorithm
Hodgkin Lymphoma ~40% - Characteristic For Reed-Sternberg (RS) Cells
lymphocyte predominant (LP ... pattern of spread, B symptoms ... Lymphoproliferative #Disorders #Classification ... #pathophysiology
Refeeding Syndrome: Pathogenesis and clinical findings

Patients at Risk of Refeeding Syndrome:
 - Little or no nutritional
- CHF - Pulmonary ... PO4 -> decr RBC ATP ... Syndrome #diagnosis #pathophysiology ... #symptoms #signs
Amyotrophic Lateral Sclerosis (ALS) Summary
ALS: combination of the clinical examination finding of amyotrophy with the pathologic
Lateral Sclerosis (ALS ... lateral sclerosis Pathophysiology ... (1) limb-onset ALS ... fasciculations Common Symptoms ... Lateral #Sclerosis #neurology
Differentiation Syndrome in APML
Epidemiology:
 • Incidence: common in APL (2-48% depending on the study)
 • Triggers:
Incidence: common in APL ... ATRA treatment Pathophysiology ... Imaging: CXR- pulmonary ... Diagnosis: >3 symptoms
Vasculitis - Differential Diagnosis Framework

When to Consider Vasculitis:
• Purpura, ischemic skin lesions
• Mononeuritis multiplex
• Hematuria, proteinuria,
Presentation: Systemic Symptoms ... affects the skin, neurologic ... • Progressive symptoms ... cognitive impairment, neurologic ... , Elevated AST ALT