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diagnosis differential rheumatology causes management algorithm apml chronic classification comparison cryofibrinogenemia differentiation fatigue infections infectiousdiseases manifestations mycobacteria myelitis neurological nontuberculous
Neurological Manifestations of Tuberculosis Spinal Arachnoiditis & Polyradiculopathy: • Subacute onset of limb weakness, bladder/bowel dysfunction, muscle
(IRIS): • In HIV ... lymphadenopathy, pulmonary ... Meningitis • Include: vasculitis ... Children with pulmonary ... differential #TB #neurology
Vasculitis and Vasculitides - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions •
progressing GN • New pulmonary ... glomerulonephritis and/or pulmonary ... Presentation - Systemic Symptoms ... Cryoglobulins • HIV ... • HBV HCV •
Causes of Fatigue - Differential Diagnosis Algorithm Endocrine • Hypo/Hyperthyroidism • Diabetes • Pituitary Insufficiency • Adrenal
Neoplastic / Hematologic ... Endocarditis • Tuberculosis ... Hepatitis • HIV ... Chronic Obstructive Pulmonary ... Disease Neurologic
Vasculitis - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions • Mononeuritis multiplex • Hematuria, proteinuria,
Presentation: Systemic Symptoms ... affects the skin, neurologic ... • Progressive symptoms ... cognitive impairment, neurologic ... Differential #Diagnosis #Rheumatology
Rhombencephalitis BACTERIAL - Listeria (biphasic illness with bulbar dysfunction occurring later) - Mycobacterium tuberculosis - Pneumococcus - Brucella - Borrelia (Lyme Disease) -
Mycobacterium tuberculosis ... Herpes Viruses (HSV ... Toxoplasmosis AUTOIMMUNE/VASCULITIS ... syndrome (bulbar symptoms ... Diagnosis #Causes #Neurology
TRALI vs TACO - Transfusion Reactions TRALI: • Epidemiology: 0.1% of transfused patientsl • Risk factors: Critical
blood donor • Pathophysiology ... : 2 hit mechanism ... ARDS to explain symptoms ... , and CXR with pulmonary ... Transfusion #Reactions #hematology
Nontuberculous Mycobacteria (NTM) Infections Mycobacterial species other than those belonging to the Mycobacterium tuberculosis complex and
Mycobacterium tuberculosis ... Advanced HIV (CD4 ... Hematologic malignancy ... gastrointestinal symptoms ... • Clinical (Symptoms
Cryofibrinogenemia Summary Cryofibrinogenemia Epidemiology: • 40-70 years with a modest female predominance Cryofibrinogenemia: • The precipitation of a
Cryofibrinogenemia Symptoms ... malignancies, vasculitis ... thrombophlebitis, pulmonary ... • TTP, HUS and HIT ... #hematology
Differentiation Syndrome in APML Epidemiology: • Incidence: common in APL (2-48% depending on the study) • Triggers:
ATRA treatment Pathophysiology ... Imaging: CXR- pulmonary ... Diagnosis: >3 symptoms ... • Steroids: IV ... diagnosis #management #hematology
Transverse Myelitis Overview Focal inflammatory disorder of the spinal cord resulting in rapid onset of weakness, sensory
monophasic Pathophysiology ... Bilateral signs and/or symptoms ... simplex virus, HIV ... - Sjogren - Vasculitis ... diagnosis #management #neurology
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