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differential symptoms disease erythematosus hematology lupus management sle systemic vasculitis behcet behcets classification criteria gap globulin monoclonal oncology paraproteinemias protein
Behçet's Syndrome Systemic disease associated with inflammation of multiple organs, small-vessel vasculitis and large-vessel vasculopathy Epidemiology: • Young
ulceration • Ocular ... disease (panuveitis, retinal ... : Giant retinal ... #signs #symptoms ... #rheumatology #
Paraproteinemias Entities That Can Feature A Monoclonal Protein/M Component: • MM • WM • MGUS • MGCS • MGRS • Splenic Marginal Zone
• MGCS • MGRS ... Hypergammaglobulinemic macular ... , retinal, DVT, ... Paraproteinemias #Hematology ... #Differential #Diagnosis
Behcet's Syndrome - Diagnosis Diagnostic Criteria for Behget's Syndrome (International Study Group for Behget's Disease): • Recurrent,
- Diagnosis Diagnostic ... disease: Uveitis or retinal ... (e.g. uveitis, retinal ... vasculitis) • Arthritis ... #criteria #rheumatology
Clinical Features of Systemic Lupus (SLE) General: Fever (50%), Depression, Fatigue (75%), Weight loss (50%) Eye: Sjögrens (15%) Skin
of hip (rare), Arthritis ... Demyelinating syndromes ... erythematosus #signs ... #symptoms #diagnosis ... #rheumatology
Rheumatoid Arthritis - Signs and Symptoms • Ocular: Keratoconjunctivitis sicca, Episcleritis, Scleritis, Scleromalacia perforans • Pulmonary:
Rheumatoid Arthritis ... - Signs and Symptoms ... • Ocular: Keratoconjunctivitis ... Thrombocytosis, Felty's syndrome ... #diagnosis #rheumatology
Vasculitis and Vasculitides - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions •
- Differential Diagnosis ... and often causes arthritis ... • Cogan Syndrome ... purpura: strong sign ... #rheumatology #
Vasculitis - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions • Mononeuritis multiplex • Hematuria, proteinuria,
- Differential Diagnosis ... pulmonary and renal ... Vasculitis Differential Diagnosis ... purpura: Strong sign ... #Rheumatology
SLE (Systemic Lupus Erythematosus) Suspect: Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
Erythematous, macular ... Differential Diagnosis ... Non-autoimmune rheumatologic ... Erythematosus #Diagnosis ... #Rheumatology
Sjogren's Syndrome Overview Epidemiology: • F > M: 9:1 • 5-6th Decades (can be any age) Autoimmune exocrinopathy multisystemic disease
Diagnosis: • Dry ... gland) biopsy • Ocular ... Arthralgia and Arthritis ... #Rheumatology # ... Diagnosis #Management
Elevated Globulin - Protein Gap (Total Protein - Albumin > 4) Work-up of an Elevated Globulin Gap: •
Gammopathy Include: • MGUS ... changes (POEMS syndrome ... (RA, Temporal arteritis ... cancers, HCC, renal ... #differential #diagnosis
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