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differential disease hematology management signs erythematosus lupus sle systemic agglutinin anemia arthritis behcet behcets classification cold criteria cryofibrinogenemia hemolytic monoclonal
Paraproteinemias Entities That Can Feature A Monoclonal Protein/M Component: • MM • WM • MGUS • MGCS • MGRS • Splenic Marginal Zone
• MM • WM • MGUS ... Autoimmunity: • -MM/WM: Vasculitis ... Vasculitis) Autoantibodies ... , retinal, DVT, ... #Differential #Diagnosis
Behcet's Syndrome - Diagnosis Diagnostic Criteria for Behget's Syndrome (International Study Group for Behget's Disease): • Recurrent,
- Diagnosis Diagnostic ... vasculitis ... (e.g. uveitis, retinal ... vasculitis) • ... #criteria #rheumatology
Behçet's Syndrome Systemic disease associated with inflammation of multiple organs, small-vessel vasculitis and large-vessel vasculopathy Epidemiology: • Young
, small-vessel vasculitis ... vasculitis) • ... meningitis), MCC CNS symptoms ... #signs #symptoms ... #rheumatology #
Vasculitis and Vasculitides - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions •
- Differential Diagnosis ... : • Behçet Syndrome ... • Cogan Syndrome ... Presentation - Systemic Symptoms ... #rheumatology #
Vasculitis - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions • Mononeuritis multiplex • Hematuria, proteinuria,
Diagnosis Framework ... pulmonary and renal ... Presentation: Systemic Symptoms ... • Progressive symptoms ... #Rheumatology
Clinical Features of Systemic Lupus (SLE) General: Fever (50%), Depression, Fatigue (75%), Weight loss (50%) Eye: Sjögrens (15%) Skin
Butterfly rash, Vasculitis ... Demyelinating syndromes ... Abdominal pain (20%) Renal ... erythematosus #signs #symptoms ... #diagnosis #rheumatology
Cold Agglutinin Disease 3 Types of Cold Sensitive Antibodies: 1. Cold Agglutinins (CAD) 2. Donath-Landsteiner
Cryoglobulins (Vasculitic ... Cold Agglutinin Syndrome ... significance (MGUS ... hemolytic #anemia #hematology ... #diagnosis
Cryofibrinogenemia Summary Cryofibrinogenemia Epidemiology: • 40-70 years with a modest female predominance Cryofibrinogenemia: • The precipitation of a
Cryofibrinogenemia Symptoms ... malignancies, vasculitis ... thrombi including retinal ... Antiphospholipid syndrome ... #rheumatology #
Rheumatoid Arthritis - Signs and Symptoms • Ocular: Keratoconjunctivitis sicca, Episcleritis, Scleritis, Scleromalacia perforans • Pulmonary:
• Ocular: Keratoconjunctivitis ... Vascular: Rheumatoid vasculitis ... Pericarditis • Renal ... Thrombocytosis, Felty's syndrome ... #diagnosis #rheumatology
SLE (Systemic Lupus Erythematosus) Suspect: Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
Erythematous, macular ... Differential Diagnosis ... Non-autoimmune rheumatologic ... Induced Lupus: • Symptoms ... #Rheumatology
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