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diagnosis differential management erythematosus hematology lupus sle systemic vasculitis arthritis autoimmune behcet classification cryofibrinogenemia disease hemeonc hemophagocytic hlh lymphohistiocytosis myopathy
Behçet's Syndrome Systemic disease associated with inflammation of multiple organs, small-vessel vasculitis and large-vessel vasculopathy Epidemiology: • Young
ulceration • Ocular ... meningitis), MCC CNS symptoms ... disease (SVC/IVC occlusion ... diagnosis #management #signs ... #symptoms #rheumatology
Cryofibrinogenemia Summary Cryofibrinogenemia Epidemiology: • 40-70 years with a modest female predominance Cryofibrinogenemia: • The precipitation of a
Cryofibrinogenemia Symptoms ... pulmonary emboli, and ocular ... thrombi including retinal ... Antiphospholipid syndrome ... Cryofibrinogenemia #diagnosis #rheumatology
Clinical Features of Systemic Lupus (SLE) General: Fever (50%), Depression, Fatigue (75%), Weight loss (50%) Eye: Sjögrens (15%) Skin
Demyelinating syndromes ... Abdominal pain (20%) Renal ... erythematosus #signs ... #symptoms #diagnosis ... #rheumatology
Vasculitis and Vasculitides - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions •
• Cogan Syndrome ... reactions, and vaso-occlusive ... Presentation - Systemic Symptoms ... purpura: strong sign ... differential #diagnosis #rheumatology
Rheumatoid Arthritis - Signs and Symptoms • Ocular: Keratoconjunctivitis sicca, Episcleritis, Scleritis, Scleromalacia perforans • Pulmonary:
and Symptoms • ... Ocular: Keratoconjunctivitis ... Pericarditis • Renal ... Thrombocytosis, Felty's syndrome ... #rheumatology
Vasculitis - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions • Mononeuritis multiplex • Hematuria, proteinuria,
pulmonary and renal ... reactions, and vaso-occlusive ... purpura: Strong sign ... • Progressive symptoms ... Differential #Diagnosis #Rheumatology
SLE (Systemic Lupus Erythematosus) Suspect: Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
Erythematous, macular ... Non-autoimmune rheumatologic ... APLA/LAC: • Renal ... Induced Lupus: • Symptoms ... Erythematosus #Diagnosis #Rheumatology
Autoimmune Myositis - Differential Diagnosis Framework Inflammatory Myopathies: Commonly symmetric proximal muscle weakness, no substantial muscle pain
RP-ILD), dermato-rheumatologic ... papules and Gottron sign ... ) • Shawl sign ... phenomenon INCLUSION ... Myositis #Myopathy #rheumatology
Relapsing Polychondritis What is it? Recurrent inflammation of the cartilage in the body (Autoimmune disorder) Who? • Most frequently: 40
ethnicities Symptoms ... + Nonspecific symptoms ... chondritis • Ocular ... Heart failure • Renal ... Polychondritis #rheumatology
Hemophagocytic Lymphohistiocytosis (HLH) High mortality without prompt recognition and management. HLH is a critical diagnostic consideration in
hyperinflammatory syndrome ... or triggers) is crucial ... Presentation • Common Signs ... and Symptoms: ... Diagnosis #Management #Hematology
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