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diagnosis differential management autoimmune erythematosus hematology lupus myositis vasculitis arthritis behcet chronic classification cll cryofibrinogenemia disease leukemia lymphocytic myopathy oncology
Clinical Features of Systemic Lupus (SLE) General: Fever (50%), Depression, Fatigue (75%), Weight loss (50%) Eye: Sjögrens (15%) Skin
Lupus (SLE) General ... Demyelinating syndromes ... Abdominal pain (20%) Renal ... #signs #symptoms ... #diagnosis #rheumatology
Behçet's Syndrome Systemic disease associated with inflammation of multiple organs, small-vessel vasculitis and large-vessel vasculopathy Epidemiology: • Young
Systemic disease ... disease (SVC/IVC occlusion ... Oral aphthae : SLE ... diagnosis #management #signs ... #symptoms #rheumatology
Autoimmune Myositis Necrotizing myopathy is associated with higher CK levels, greater level of muscle weakness, less systemic
weakness, less systemic ... symptoms, and less ... anti-synthetase syndrome ... Can also see mechanics ... Myositis #diagnosis #rheumatology
Vasculitis and Vasculitides - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions •
reactions, and vaso-occlusive ... Symptoms (Sx) in ... purpura: strong sign ... vasculitis, and SLE ... differential #diagnosis #rheumatology
Cryofibrinogenemia Summary Cryofibrinogenemia Epidemiology: • 40-70 years with a modest female predominance Cryofibrinogenemia: • The precipitation of a
Cryofibrinogenemia Symptoms ... processes: • Systemic ... pulmonary emboli, and ocular ... thrombi including retinal ... Antiphospholipid syndrome
SLE (Systemic Lupus Erythematosus) Suspect: Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
SLE (Systemic Lupus ... Erythematous, macular ... Non-autoimmune rheumatologic ... APLA/LAC: • Renal ... Induced Lupus: • Symptoms
Vasculitis - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions • Mononeuritis multiplex • Hematuria, proteinuria,
diseases, such as SLE ... reactions, and vaso-occlusive ... Symptoms (SX) in ... purpura: Strong sign ... Differential #Diagnosis #Rheumatology
Chronic Lymphocytic Leukemia - Summary Cancer affecting lymphocytes/Mature B cell neoplasm • Lymphocytes accumulate in large numbers
rendering the immune system ... non-Hodgkin lymphoma SLL ... with no early symptoms ... Physical Exam/Signs ... ’s CLL Scoring system
Rheumatoid Arthritis - Signs and Symptoms • Ocular: Keratoconjunctivitis sicca, Episcleritis, Scleritis, Scleromalacia perforans • Pulmonary:
and Symptoms • ... Ocular: Keratoconjunctivitis ... Pericarditis • Renal ... Thrombocytosis, Felty's syndrome ... #rheumatology
Sjogren's Syndrome Overview Epidemiology: • F > M: 9:1 • 5-6th Decades (can be any age) Autoimmune exocrinopathy multisystemic disease
overlaps with RA, SLE ... gland) biopsy • Ocular ... Central nervous system ... Cytopenia: 2% Systemic ... #Rheumatology #
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