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diagnosis management differential signs erythematosus hematology systemic ana anca antibodies antibody antineutrophil antinuclear arthritis behcet classification cryofibrinogenemia disease diseases monoclonal
Clinical Features of Systemic Lupus (SLE) General: Fever (50%), Depression, Fatigue (75%), Weight loss (50%) Eye: Sjögrens (15%) Skin
(SLE) General: ... Butterfly rash, Vasculitis ... Demyelinating syndromes ... erythematosus #signs #symptoms ... #diagnosis #rheumatology
Behçet's Syndrome Systemic disease associated with inflammation of multiple organs, small-vessel vasculitis and large-vessel vasculopathy Epidemiology: • Young
meningitis), MCC CNS symptoms ... disease (SVC/IVC occlusion ... Oral aphthae : SLE ... • Arthritis: SLE ... #rheumatology #
Vasculitis and Vasculitides - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions •
such as systemic lupus ... reactions, and vaso-occlusive ... Presentation - Systemic Symptoms ... , and SLE) • Urinalysis ... differential #diagnosis #rheumatology
SLE (Systemic Lupus Erythematosus) Suspect: Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
SLE (Systemic Lupus ... Erythematous, macular ... Non-autoimmune rheumatologic ... APLA/LAC: • Renal ... : • Symptoms limited
ANA (Antinuclear Antibody) and ANCA (Antineutrophil cytoplasmic antibodies) • Systemic lupus erythematosus 1. Anti-dsDNA
) • Systemic lupus ... in drug-induced SLE ... cases • Sjögren syndrome ... vasculitis - MPO ... antibodies #diagnosis #rheumatology
Vasculitis - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions • Mononeuritis multiplex • Hematuria, proteinuria,
pulmonary and renal ... diseases, such as SLE ... reactions, and vaso-occlusive ... • Progressive symptoms ... Differential #Diagnosis #Rheumatology
Cryofibrinogenemia Summary Cryofibrinogenemia Epidemiology: • 40-70 years with a modest female predominance Cryofibrinogenemia: • The precipitation of a
Cryofibrinogenemia Symptoms ... malignancies, vasculitis ... pulmonary emboli, and ocular ... thrombi including retinal ... Antiphospholipid syndrome
Paraproteinemias Entities That Can Feature A Monoclonal Protein/M Component: • MM • WM • MGUS • MGCS • MGRS • Splenic Marginal Zone
Autoimmunity: • -MM/WM: Vasculitis ... Vasculitis) Autoantibodies ... to cold IgG • Lupus ... , retinal, DVT, ... Paraproteinemias #Hematology
Rheumatoid Arthritis - Signs and Symptoms • Ocular: Keratoconjunctivitis sicca, Episcleritis, Scleritis, Scleromalacia perforans • Pulmonary:
• Ocular: Keratoconjunctivitis ... Vascular: Rheumatoid vasculitis ... Pericarditis • Renal ... Thrombocytosis, Felty's syndrome ... #diagnosis #rheumatology
Sjogren's Syndrome Overview Epidemiology: • F > M: 9:1 • 5-6th Decades (can be any age) Autoimmune exocrinopathy multisystemic disease
overlaps with RA, SLE ... gland) biopsy • Ocular ... ) • Cutaneous vasculitis ... : 2% Systemic Vasculitis ... #Rheumatology #
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