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diagnosis rheumatology differential erythematosus lupus management symptoms systemic behcet causes classification disease edema facial hematuria nephrology renal sjogrens swelling urine
Behçet's Syndrome Systemic disease associated with inflammation of multiple organs, small-vessel vasculitis and large-vessel vasculopathy Epidemiology: • Young
, small-vessel vasculitis ... vasculitis) • ... Oral aphthae : SLE ... : SLE, Reactive ... diagnosis #management #signs
Vasculitis and Vasculitides - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions •
gastrointestinal, and/or central ... purpura: strong sign ... pulses, bruis, or blood ... Large Vessel: Blood ... , and SLE) • Urinalysis
Clinical Features of Systemic Lupus (SLE) General: Fever (50%), Depression, Fatigue (75%), Weight loss (50%) Eye: Sjögrens (15%) Skin
Butterfly rash, Vasculitis ... of hip (rare), Arthritis ... Demyelinating syndromes ... Glomerulonephritis Myositis(5%) Blood ... erythematosus #signs
Vasculitis - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions • Mononeuritis multiplex • Hematuria, proteinuria,
pulmonary and renal ... diseases, such as SLE ... purpura: Strong sign ... pulses, bruits, or blood ... Angiitis of the Central
Facial Swelling - Differential Diagnosis Framework for Facial Edema Infectious: • Dental abscess • Ludwig's angina • Vincent's angina • Cellulitis •
Autoimmune: • SLE ... Trauma: • Ocular ... Subcutaneous emphysema Renal ... internal jugular vein ... Differential #Diagnosis #PhysicalExam
Hematuria - Differential Diagnosis Framework Gross Hematuria: Red/Dark urine • 1ml blood/liter urine can induce color change
urine • 1ml blood ... hematuria • Signs ... Diagnostic of GN or vasculitis ... vein thrombosis ... #urine #blood
SLE (Systemic Lupus Erythematosus) Suspect: Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
Erythematous, macular ... ANCA-associated vasculitis ... APLA/LAC: • Renal ... artery or vein ... thrombosis • Pelvic vein
Sjogren's Syndrome Overview Epidemiology: • F > M: 9:1 • 5-6th Decades (can be any age) Autoimmune exocrinopathy multisystemic disease
overlaps with RA, SLE ... gland) biopsy • Ocular ... Involvement: • Central ... ) • Cutaneous vasculitis ... Arthralgia and Arthritis
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